We present our on-going works with current and former colleagues at Penn State (L.Q. Chen, W.M. Feng, S. Hu, Z.K. Liu, P. Yu, X. Wang and J. Zhang) on the numerical algorithms for the phase field simulations of some interface problems, ranging from microstructure evolution in multicomponent alloy to multicomponent lipid vesicles. We discuss recent development of highly adaptive computational al...

beta-amino acids have been employed in the past as bifunctional building blocks in intramolecular Ugi multicomponent reactions to yield beta-lactam derivatives. By using 7-azabicyclo[2.2.1]heptane-2-carboxylic acid, a different outcome has been observed and rationalised. The final compounds are polyfunctionalised azabicyclic peptidomimetics, and further elaboration can be achieved exploiting an...

Seismic images obtained by multicomponent wave-equation migration can be decomposed into angle-gathers with a transformation that generalizes the equivalent construction for primary waves. A particularly simple formulation is to use all three components of the offset vector separating sources and receivers at image points. Using full vector offsets, multicomponent angle-gathers are built using ...

Multicomponent signals consist of several traits that are perceived as a whole. Although many animals rely on multicomponent signals to communicate, the selective pressures shaping these signals are still poorly understood. Previous work has mainly investigated the evolution of multicomponent signals by studying each trait individually, which may not accurately reflect the selective pressures e...

Background Treatment of childhood obesity is important in preventing development of obesity-related diseases later in life. This systematic review evaluates the effect of multicomponent lifestyle interventions for children and adolescents from 2 to 18 years. Methods and Results We performed systematic searches in nine databases. Thirty-nine studies met the criteria for meta-analyses. We found...

We study the equilibrium sediment of a multicomponent system of charged colloids using primitive model Monte Carlo simulations, which include counterions explicitly. We find separation of the different colloidal components into almost pure layers, where colloids with large charge-to-mass ratio sediment higher in the sample. This effect appears due to a competition between ionic entropy, gravita...

Many everyday situations require the flexible interruption and changing of different actions to achieve a goal. Several strategies can be applied to do so, but those requiring high levels of cognitive control seem to confer an efficiency (speed) advantage in situations requiring multi-component behavior. However, it is elusive in how far personality traits affect performance in such situations....

A novel chemoenzymatic one-pot multicomponent synthesis of thiazole derivatives was developed. A series of thiazole derivatives were synthesized with high yields up to 94% under mild enzyme-catalyzed conditions. The blank and control experiments reveal that trypsin from porcine pancreas (PPT) displayed great catalytic activity to promote this reaction and showed a wide tolerance range towards d...

In this paper we discuss the dispersionless limit of the multicomponent 2D Toda hierarchy. The discrete flows of the hierarchy are used to define charge preserving Lax and Orlov–Schulman operators. This construction allows us to perform two types of dispersionless limits, one type leads to the 0-genus universal Whitham hierarchy while the other leads to a dispersionless hierarchy which contains...

Biological processes are often governed by functional modules of large protein assemblies such as the proteasomes and the nuclear pore complex, for example. However, atomic structures can be determined experimentally only for a small fraction of these multicomponent assemblies. In this article, we present an ant colony optimization based approach to predict the structure of large multicomponent...