Recently, a multicenter randomized controlled trial (RCT) by Cooper and colleagues indicated that decompressive craniectomy (DC) may be associated with a worse functional outcome in patients with diffuse traumatic brain injury (TBI), although DC can immediately and constantly reduce intracranial pressure (ICP). As this trial is well planned and of high quality, the unexpected result is meaningf...

A standardized neurologic assessment scoring instrument was developed and tested for use in a multicenter trial of hypervolemic hemodilution in acute hemispheric stroke. Components of the neurologic examination pertinent to hemispheric stroke syndromes were emphasized. The scale was evaluated using 16 acute stroke patients for concurrent validity (Pearson coefficient r = 0.89 compared with glob...

This study reports the use of multicenter bond indices as a new tool for the quantitative characterization of homoaromaticity. The approach was applied to the series bicyclic systems whose homoaromaticity was recently discussed in terms of traditional aromaticity index, namely, NICS. In this study we found that the multicenter bond indices are indeed able to quantify the degree of homoaromatici...

Peer-reviewed Study Purpose of Study Duration of Use Compliance Results Primary Finding Quadruple Hamstring Anterior Cruciate Ligament Reconstruction; A Multicenter Study: Scranton et al (2002, J. Arthroc. & Rel Surg). This study evaluated the ACL repair technique and the standardization of a rehabilitation technique. Not reported. Not reported. The multicenter study reported success with this ...

AIMS The aim is to study the prevalence and possible relationship of apathy and leukoaraiosis in cases of cognitive impairment of varying severity in Spain. METHODS We conducted a cross-sectional, descriptive, multicenter study involving 109 patients with Alzheimer's disease (AD) and 59 with mild cognitive impairment (MCI). RESULTS The older group with AD had a higher prevalence of leukoara...

Lymphocyte proliferation assays (LPAs) are widely used to assess T-lymphocyte function of patients with human immunodeficiency virus infection and other primary and secondary immunodeficiency disorders. Since these assays require expertise not readily available at all clinical sites, specimens may be shipped to central labs for testing. We conducted a large multicenter study to evaluate the eff...

Citation: de Heer EW, Dekker J, Beekman ATF, van Marwijk HWJ, Holwerda TJ, Bet PM, Roth J, Timmerman L and van der Feltz-Cornelis CM (2018) Comparative Effect of Collaborative Care, Pain Medication, and Duloxetine in the Treatment of Major Depressive Disorder and Comorbid (Sub)Chronic Pain: Results of an Exploratory Randomized, Placebo-Controlled, Multicenter Trial (CC:PAINDIP). Front. Psychiat...

Multicenter supergravity solutions corresponding to Higgs phases of supersymmetric Yang–Mills theories are considered. For NS5 branes we identify three cases where there is a description in terms of exact conformal field theories. Other supergravity solutions, such as D3-branes with angular momentum, are understood as special limits of multicenter ones. Within our context we also consider 4-dim...

Investigators from the International Pediatric Stroke Study Group (IPSS) reviewed data a multicenter observational cohort of neonates and children with stroke, comparing clinical features outcomes differentiating posterior circulation arterial ischemic stroke (PCAIS) anterior (ACAIS).

Purpose: To explore the level of and the experiences with spiritual care by nurses in curative cancer care. Methods: In this mixed-method study, nurses were recruited in eight hospitals in The Netherlands. Questionnaire scores were quantitatively analyzed (n=57), and concerned a spirituality and a competence scale, and five questions about spiritual care. Because of data saturation, qualitativ...