The transmembrane domains (TMD) in membrane receptors play a key role in cell signaling. As previously shown by us a peptide targeting the TMD of neuropilin-1 (MTP-NRP1), blocks cell proliferation, cell migration and angiogenesis in vitro, and decreases glioblastoma growth in vivo. We now explored the clinical potential of MTP-NRP1 on breast cancer models and demonstrate that MTP-NRP1 blocks pr...

BACKGROUND Myofascial pain syndrome is a significant source of mechanical pain. The aim of this study was to investigate the effects of arm movement on reaction time in females with latent and active upper trapezius myofascial trigger point. METHODS In this interventional study, a convenience sample of fifteen women with one active MTP, fifteen women with one latent MTP in the upper trapezius...

Abstrctct-The problem of base station antenna assignment (BSAA) with minimum mobile transmit power (MTP) is studied for CDMA networks that employ fixed overlapping sector antenna architecture (FOSAA). I t is noted that the non-FOSAA has limitations in switching users between incell sectors and also out-of-cell sectors in moderately-loaded networks. I t is then shown that by employing overlappin...

A massive transfusion protocol (MTP) in which most non-RBC transfusions were laboratory result-driven was updated to a 1:1:1 RBC/plasma/platelet formula-driven protocol. Platelet count, fibrinogen level, and prothrombin time (PT) were monitored. In the patients who survived the first 12 hours, the results of coagulation tests were analyzed. Irrespective of the MTP or transfused RBC/plasma ratio...

In order to establish a highly efficient P system for resolving clustering problems and overcome the computation incompleteness implementation difficulty of systems, an attractive membrane system, integrated with enhanced particle swarm optimization (PSO) based on environmental factors crossover operators distributed parallel computing model monodirectional tissue-like systems (MTP), is constru...

BACKGROUND Small-scale micro-bioreactors have become the cultivation vessel of choice during the first steps of bioprocess development. They combine high cultivation throughput with enhanced cost efficiency per cultivation. To gain the most possible information in the early phases of process development, online monitoring of important process parameters is highly advantageous. One of these impo...

background: myofascial pain syndrome is a significant source of mechanical pain. the aim of this study was to investigate the effects of arm movement on reaction time in females with latent and active upper trapezius myofascial trigger point. methods: in this interventional study, a convenience sample of fifteen women with one active mtp, fifteen women with one latent mtp in the upper trapezius...

Min. hip  – – 0.12 0.11 0.06 0.22 – – – – – – Min. knee  – – – – 0.15 0.28 – – 0.11 0.17 0.10 0.17 Min. ankle  0.06 –0.06 – – 0.10 0.30 0.10 –0.05 – – – – Min. MTP  0.15 0.20 – – 0.05 0.17 0.10 0.09 – – – – Min. rotation  – – – – – – – – 0.14 0.22 0.15 0.17 Total  swept hip – – – – 0.09 0.16 – – – – – – Total  swept knee – – – – – – – – 0.08 0.17 0.07 0.20 Total  swept ankle 0.10 –0.04 ...

PURPOSE The purpose of this retrospective study is to clarify the difference in plantar pressure distribution during walking and related patient-based outcomes between forefoot joint-preserving arthroplasty and resection-replacement arthroplasty in patients with rheumatoid arthritis (RA). METHODS Four groups of patients were recruited. Group1 included 22 feet of 11 healthy controls (age 48.6 ...

Chemotherapeutic agents have been shown to enhance the antitumor activity of biological response modifiers and cytokines in rodents and humans. The purpose of this study was 2-fold: (a) to determine whether doxorubicin (DOX) would enhance or interfere with the effect of muramyl dipeptide and lipopolysaccharide on canine monocyte activation as measured by an in vitro WEHI-164 cell cytotoxicity a...