AIM Short-term and long-term evaluation of the effect of whole human blood or serum contamination on the surface microhardness value and microstructure of white and grey mineral trioxide aggregate (MTA). METHODOLOGY Three groups of 10 samples for each type of MTA were prepared. The first group was mixed with and exposed to fresh whole human blood. The second and third groups were mixed with d...

Objective The aim of this study was to evaluate and compare, both clinically and radiographically, the effects of calcium silicate-based materials (i.e., ProRoot MTA [PR-MTA], MTA-Plus [MTA-P], and Biodentine [BD]) and ferric sulfate [FS] in pulpotomy of primary molars. Materials and Methods In this randomized clinical trial, 29 healthy 5- to 7-year-old children with at least four carious pri...

OBJECTIVE This study was aimed to evaluate and to compare the push-out bond strength of different brands of mineral trioxide aggregate (MTA) with a calcium enriched mixture cement (CEM). MATERIALS AND METHODS Fifteen extracted, single-rooted human teeth were used. The middle-third of the roots were sliced perpendicular to the long axis into 1.00 ± 0.05 mm thick serial slices (15 root × 4 slic...

AIM To compare the histomorphological response of rat dental pulps capped with MM-MTA and ProRoot MTA at 1, 2 and 4 weeks postoperatively. MATERIALS AND METHODS Direct pulp capping with MM-MTA and ProRoot MTA, overlaid with light-cured composite resin, was performed on right and left maxillary first molars of 20 Wistar rats. Animals were killed at 1, 2 and 4 weeks postoperatively. Biopsy samp...

OBJECTIVES An unsuccessful attempt to reach the apical area or to place the retrograde material is a major difficulty in periradicular surgery. The aim of this study was to compare the histological evaluation of the healing process following an orthograde versus a retrograde application of mineral trioxide aggregate (MTA) as a root-end filling material during apical surgery on cats' teeth in or...

BACKGROUND Inflammation and fibrogenesis are directly related to chronic liver disease progression, including hepatocellular carcinoma (HCC) development. Currently there are few therapeutic options available to inhibit liver fibrosis. We have evaluated the hepatoprotective and anti-fibrotic potential of orally-administered 5'-methylthioadenosine (MTA) in Mdr2(-/-) mice, a clinically relevant mo...

The antifungal action of different concentrations of white-colored mineral trioxide aggregate (MTA) against Candida albicans was assessed in vitro. Fresh mix of MTA was prepared at concentrations varying from 0.78 mg/ml to 50 mg/ml by dilution with 10 ml molten agar at 45 degrees C. The MTA-agar compound was thoroughly mixed and the uniform mix was then poured into sterile Petri dishes and allo...

Mineral trioxide aggregate (MTA) restoratives and MTA sealers are commonly used in endodontics. Commonly referenced standards for testing of MTA are ISO 6876, 9917-1 and 10993. A PubMed search was performed relating to the relevant tests within each ISO and "mineral trioxide aggregate". MTA restoratives are typically tested with a mixture of tests from multiple standards. As the setting of MTA ...

The purpose of this study was to analyze the physical properties and chemical compositions of a new experimental cement (NEC) and compare them with mineral trioxide aggregate (MTA); pH, working time, setting time, dimensional changes following setting, flow, film thickness, and chemical composition of NEC and MTA were assessed. For chemical compositions, all specimens were imaged and analyzed b...

This paper aims to review the biological and physicochemical properties of mineral trioxide aggregate (MTA) with respect to its ability to induce reparative dentinogenesis, which involves complex cellular and molecular events leading to hard-tissue repair by newly differentiated odontoblast-like cells. Compared with that of calcium hydroxide-based materials, MTA is more efficient at inducing re...