Only limited data are available regarding myocardial iron overload in adult patients with transfusion dependent acquired anemias. To address this topic using MRI T2* we studied 27 consecutive chronic transfusion dependent patients with acquired anemias: (22 myelodysplastic syndrome, 5 primary myelofibrosis). Cardiac MRI T2* values obtained ranged from 5.6 to 58.7 (median value 39.8) millisecond...

Abstract Background and aim Despite improvements in the imaging modalities, optimal protocol for extracranial facial nerve using 1.5 T MRI is still debatable. Pre-operative mapping of could provide valuable information surgeons. The current study aimed to evaluate choose proper protocols segment pre-op imaging. Patients methods Extracranial nerves on tumoral normal side 19 patients (38 nerves) ...

BACKGROUND AND PURPOSE It is generally considered that tissue that appears abnormal on T2 MRI is already infarcted and that any penumbra lies outside the T2-visible lesion. We investigated the distribution of infarcted tissue using proton spectroscopic MRI. METHODS In patients with symptoms of acute hemispheric ischemic stroke, imaged within a maximum of 3 days of stroke, we explored the dist...

PURPOSE Using magnetic resonance imaging (MRI), residual tumor cannot be differentiated from nonspecific postoperative changes in operated patients with brain gliomas. The higher specificity and sensitivity of L-(methyl-11C)-labeled methionine positron emissions tomography (MET-PET) in gliomas has been demonstrated in previous studies and is the rationale for the integration of this investigati...

BACKGROUND In the UK, prostate cancer (PC) is the most common cancer in men. A diagnosis can be confirmed only following a prostate biopsy. Many men find themselves with an elevated prostate-specific antigen (PSA) level and a negative biopsy. The best way to manage these men remains uncertain. OBJECTIVES To assess the diagnostic accuracy of magnetic resonance spectroscopy (MRS) and enhanced m...

STUDY DESIGN This was a single surgeon, single center-based retrospective study with prospective data collection. PURPOSE To assess the correlation between T2-weighted magnetic resonance imaging (MRI) signal intensity (SI) changes and factors such as age, duration of symptoms, baseline modified Japanese Orthopedic Association (mJOA) score and to determine its prognostic value in predicting re...

OBJECTIVES We sought to evaluate whether echocardiographic diastolic function indices correlate with myocardial iron and systolic function in patients with transfusion-dependent thalassemia (TDT) who are at risk for cardiomyopathy. BACKGROUND In thalassemia syndromes, there is an important clinical need to risk stratify patients for the development of iron-overload cardiomyopathy so that chel...

Modic et al. in 1988 first described characteristic MRI changes in the vertebral body bone marrow and endplates, adjacent to degenerating intervertebral (iv) discs. Depending on the changes in T1 and T2 MRI signals, three types of lesions were identified: Type I lesions (low T1 and high T2 signal) are thought to be clinically active, due to increased blood flow within the bone. Type II lesions ...

Zntrodzzction Focused ultrasound (FUS) has the potential to noninvasively treat cancer by selectively producing damage within a predetermined volume, without damaging overlying tissue. The feasibility of using MRI for guiding and monitoring FUS tissue damage has been previously investigated [l-2]. T2-weighted MRI appears to be especially promising for evaluation of the ultrasonic lesions. The p...