Mowat-Wilson syndrome (MOWS) is caused by de novo heterozygous mutation at ZEB2 (SIP1, ZFHX1B) gene, and exhibit moderate to severe intellectual disability (ID), a characteristic facial appearance, epilepsy and other congenital anomalies. Establishing a murine MOWS model is important, not only for investigating the pathogenesis of this disease, but also for identifying compounds that may improv...

Mowat, A. P., Psacharopoulos, H. D., and Williams, R. (1976). Archives of Disease in Childhood, 51, 763. Extrahepatic biliary atresia versus neonatal hepatitis: review of 137 prospectively investigated infants. In a prospective regional survey of neonatal hepatitis syndrome 32 infants had extrahepatic biliary atresia (EHBA) and 103 had hepatitis. No cause for the lesion was found in infants wit...

Behret (1937) described a chronic, relapsing complex of oral ulceration, genital ulceration, and ocular inflammation. It has been recognized that many other systems may be involved, including the skin, cardiovascular, central nervous, and gastrointestinal systems, and the joints, together with venous thrombosis (Enoch, 1969; Mason and Barnes, 1969; Mowat and Hothersall, 1969); Francis, 1970; Ka...

Working memory is often defined in cognitive psychology as a system devoted to the simultaneous processing and maintenance of information. In line with the time-based resource-sharing model of working memory (TBRS; Barrouillet and Camos, 2015; Barrouillet et al., 2004), there is accumulating evidence that, when memory items have to be maintained while performing a concurrent activity, memory pe...

tion. There have also been significant advances in the This commentary by the late Alex P. Mowat reflects his management of complications of chronic cholestasis extensive knowledge and experience in pediatric liver disand in some complications of cirrhosis. We have reason ease; its genesis reflects his commitment to education as well as his personal qualities. Dr. Mowat had presented an to cong...

Fig 1. Intestinal immune system. The default response to harmless antigens in the gut is the induction of a state of immunological hyporesponsiveness, known as oral tolerance, and this may be the homeostatic mechanism that prevents intestinal disorders such as celiac disease and Crohn’s disease, as well as atopy. According to Mowat, the way in which antigen is presented to the immune system is ...