For over a century, non-virus microorganisms, notably bacteria have been implicated as causal agents of cancers, a relatively small number of researchers have provided evidence to support the so-called "cancer germ" hypothesis. With the exception of the link between Helicobacter pylori and stomach cancer, other supposed links have been ignored. A wide range of bacteria and other non-virus micro...

BACKGROUND After establishment of a cell culture, inhomogenous growth and cell selection takes place at early passages. Reproducing the same confluence state among experiments might be difficult. MATERIALS AND METHODS Here we used cDNA arrays to compare the global gene expression pattern of two oral cancer cell lines at 80%, 100% and super-confluence stages. Also, the stability of the global ...

intracranial gliosis has no typical clinical signals or imaging characteristics. therefore, it can be easily misdiagnosed as neoplasm. hereby, we report a unique case of gliosis that grew outward from the surface of the brain. mri depicted its signal and enhancement pattern similar to the cerebral gray matter. the diagnosis was confirmed by pathology and immunohistochemistry. although it was di...

Serous cystic neoplasms of the pancreas are rare exocrine pancreatic neoplasms, most of which are benign and do not communicate with the pancreatic duct. Pancreatic intraepithelial neoplasm (PanIN) is considered a precursor of ductal adenocarcinoma that is microscopically recognized in pancreatic ducts. A 67-year-old Japanese woman presented with a 10-mm multilocular cystic lesion at the pancre...

Most ovarian neoplasms are benign, epithelial types are commonest. There is no regular screening test for detecting malignant ovarian neoplasm, most patients remain asymptomatic until late stages. About 80% of malignant ovarian neoplasm present in stage 3 and 4 with 15% 5 year survival rate. To find out frequency of different types of ovarian neoplasm among women aged 15-60 years and correlates...

Introduction: Chronic sclerosing sialadenitis is a relatively uncommon disorder of the salivary gland. Because of its clinical similarity to a salivary gland neoplasm, this condition has been known as Kuttner tumor and is classified as a tumorlike lesion. Case Report: This is the first reported case of bilateral Kuttner tumor of the submandibular glands in Iran. It was initially diagnosed as...

background: improvements in imaging techniques has led to an increase in the number of diagnosed pancreatic cysts. although most of the detected cases are benign, a significant percentage of them are malignant or are potentially malignant. currently, endosonography, and analysis of cyst morphology, fine needle aspiration (fna) of the cyst contents, and measurement of the amylase and carcinoembr...

Jumonji domain-containing protein 6 (JMJD6) is a non-heme Fe(II) 2-oxoglutarate (2OG)-dependent oxygenase with arginine demethylase and lysyl hydroxylase activities. Its initial discovery as a dispensable phosphatidylserine receptor (PSR) in the cell membrane of macrophages for phagocytosis was squashed by newer studies which revealed its nuclear localization and bifunctional enzymatic activity...

  Chloroma or granulocytic sarcoma (GS) is a malignant neoplasm of myeloid lineage that occur in a variety of anatomic sites other than the bone marrow including soft tissue, bone, lymph node, nasal fossa, skin and sometime in the orbit. In the subconjunctiva it is rarely reported. A 4-year-old girl with a history of treated acute myelogenous leukemia was referred to Farabi Eye Hospital, Tehra...