BACKGROUND Moringa stenopetala has been used in traditional health systems to treat diabetes mellitus. One of the successful methods to prevent of the onset of diabetes is to control postprandial hyperglycemia by the inhibition of α-glucosidase and pancreatic α-amylase activities, resulting in the aggressive delay of the carbohydrate digestion of absorbable monosaccharides. The aim of the prese...

Cancer radiotherapy aims to effectively kill tumor cells but inexorably damages normal tissues which is undesirable. The success of radiotherapy lies in sparing normal tissues from radiation damage. Natural phytochemicals possess attribute which might protect normal cells but enhance tumor cell susceptibility followed by radiotherapy through modulating cellular molecular targets. Previous resul...

Moringa oleifera Lam (Moringaceae) is promising plant for biomedicine applications because it has an impressive range of medicinal purposes with high nutritional value. Therefore, we investigated the therapeutic effect of Moringa oleifera leaf extract (MOLE) on Ehrlich's solid tumor implanted mice (EST-mice). Swiss male albino mice were implanted intramuscularly with Ehrlich ascites carcinoma (...

Chronic hyperglycemia is an indicator of diabetes mellitus and chronic dyslipidemia a risk factor cardiovascular disease. OBJECTIVE: We aim at evaluating the effect of Moringa oleifera on glucose level, lipid profile, cardiac markers, liver enzymes, proteins and histology of the heart and liver. METHODOLOGY: Twenty six male (26) adult Wistar rats were enrolled for the study. Acclimatized and ra...

The water available for daily consumption may be contaminated by natural sources or by industrial effluents. One such a contaminant is fluoride. Exposure to fluoride in drinking water has a number of adverse effects on human health. One of the naturally available alternatives for defluoridation of water is Moringa Oleifera. Using colourimetric method, tests were conducted to get optimal values ...

Consumption of Moringa oleifera leaves is a local and inexpensive solution to iron and zinc deficiencies in the Far-north region of Cameroon. However, traditional household's cooking techniques result in sauces with high pH levels and low leaves incorporation rates that compromise the bioavailability of iron and zinc. The aim of our study was to investigate the effect of modifying a standard Mo...

Diabetes mellitus is an endocrine disease of multiple aetiologies in insulin secretion. A deficiency in insulin results in hyperglycemia with metabolic disturbances of biomolecules. Moringa oleifera (MO) is endemic in the tropics with a variety of ethnomedicinal importance. The leaf of this plant has been reported to possess antioxidant and medicinal properties that may be helpful in the treatm...

In this study we investigated the anti-cancer effect of Moringa oleifera leaves, bark and seed extracts. When tested against MDA-MB-231 and HCT-8 cancer cell lines, the extracts of leaves and bark showed remarkable anti-cancer properties while surprisingly, seed extracts exhibited hardly any such properties. Cell survival was significantly low in both cells lines when treated with leaves and ba...

Pyrexia and inflammation are indicatives of various disorders. Modern medicines are available for treatment of pyrexia, but they have few side effects. Several studies are ongoing Worldwide to search natural antipyretic agents with better efficacy and fewer or no side effects. This study was aimed at evaluating the antipyretic activity of Moringa oleifera bark in rabbits against E. coli induced...