BACKGROUND Most evidence of target-organ damage in hypertension (HTN) is related to the kidneys and heart. Cerebrovascular and cognitive impairment are less well studied. Therefore, this study analyzed changes in cognitive function in patients with different stages of hypertension compared to nonhypertensive controls. METHODS AND RESULTS In a cross-sectional study, 221 (71 normotensive and 15...

Question In adults with cognitive impairment or memory problems how effective is the MoCA (Montreal Cognitive Assessment) compared to the MMSE (Mini Mental State Examination) in memory management / managing cognitive impairment? Evidence from six diagnostic test accuracy studies indicated that the MoCA is likely to perform as well as or better than the MMSE for the diagnosis of cognitive impair...

INTRODUCTION Schizophrenia (Sch) is a complex neurodevelopmental disorder associated with impairment of cognitive function as a central feature, which is confirmed by a number of studies performed on patients suffering from Sch, where clinical symptoms and social functioning of patients are consequences of neurocognitive deficits. GOAL The goal of this study was to assess the clinical usabili...

background: because of well-established role of obesity in brain lesions, progressing cognitive deficits in obese patients has been recently suggested. in current study and for the first time, we aimed to assess cognition status in iranian obese people and to compare it with non-obese individuals. methods: one hundred and eighteen consecutive patients with the different cardiovascular and metab...

BACKGROUND We examined the discriminant validity of the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE) in detecting multiple-domain mild cognitive impairment (md-MCI) in a Chinese sub-sample drawn from elderly population-based study. METHODS This study included Chinese participants from the Epidemiology of Dementia in Singapore (EDIS) study aged ≥ 60 years w...

Cognitive impairment is common in Parkinson's disease (PD). There is a critical need for a brief, standard cognitive screening measure for use in PD trials whose primary focus is not on cognition. The Parkinson Study Group (PSG) Cognitive/Psychiatric Working Group formed a Task Force to make recommendations for a cognitive scale that could screen for dementia and mild cognitive impairment in cl...

BACKGROUND/AIMS Many cognitive screening instruments (CSI) are available to clinicians to assess cognitive function. The optimal method comparing the diagnostic utility of such tests is uncertain. The effect size (Cohen's d), calculated as the difference of the means of two groups divided by the weighted pooled standard deviations of these groups, may permit such comparisons. METHODS Datasets...

Background. Sparse data limit the interpretation of Montreal Cognitive Assessment (MoCA) scores, particularly in minority populations. Additionally, there are no published data on how MoCA scores compare to the widely used Modified Mini Mental State Examination (3MSE). We provide performance data on the MoCA in a large cohort of African Americans and compare 3MSE and MoCA scores, providing a "c...

To date, there has not been a time-efficient and resource-conscious way to identify cognitive impairment in patients with substance use disorders (SUDs). In this study, we assessed the validity, accuracy, and clinical utility of a brief (10-min) screening instrument, the Montreal Cognitive Assessment (MoCA), in identifying cognitive impairment among patients with SUDs. The Neuropsychological As...

PURPOSE Persons with mild cognitive impairment (PwMCI) are at a higher risk of developing dementia than those without cognitive impairment. This research study aims to evaluate the effectiveness of a holistic health group intervention, which is based on the holistic brain health approach as well as an Eastern approach to health care, on improving the cognitive ability of Chinese PwMCI. RESEAR...