Background: Gold nanoparticles (GNPs) are among the most promising radiosensitive materials in radiotherapy. Studying the effective sensitizing factors such as nanoparticle size, concentration, surface features, radiation energy and cell type can help to optimize the effect and possible clinical application of GNPs in radiation therapy. In this study, the radiation sensitive polymer gel was use...

Three-dimensional (3D) gel dosimetry has a unique role to play in safeguarding conformal radiotherapy treatments as the technique can cover the full treatment chain and provides the radiation oncologist with the integrated dose distribution in 3D. It can also be applied to benchmark new treatment strategies such as image guided and tracking radiotherapy techniques. A major obstacle that has hin...

Three-dimensional Monte Carlo simulations of flexible and semiflexible polymer brushes at various grafting densities are carried out to study their equilibrium structure and attendant properties by using the bond fluctuation model. Our simulation results of long flexible polymer brushes are, in general, consistent with predictions of the self-consistent field theory. However, a depletion layer ...

Proton pencil beam scanning is a dynamic delivery technique with excellent conformability to the tumor volume. The accuracy of spot size and positions will have significant effect on delivered dose distribution. We employed polymer gel dosimeters measure for Shanghai Advanced Therapy facility (SAPT). Polymer (MAGAT-f PAGAT) were utilized full width at half maximum (FWHM) various depths basis th...

background: two protocols of aapm tg-51 and iaea trs-398 were compared followed by a measurement and monte carlo simulation of beam quality correction factor, kq, aapm tg-51 and iaea trs-398 protocols were compared for the absorbed dose to water for dw, and kq parameters. materials and methods: dose measurements by either protocols were performed with cylindrical and plane parallel chambers for...

Monte Carlo techniques have become popular in different areas of medical physics over the last 50 years. Factors which have contributed to the wider use include the improved description of radiation transport as well as the optimization of the computing systems. The main advantage of Monte Carlo methodology deals with the simulation of stochastic processes involving random behavior and the quan...

Introduction Polymer gel dosimeters offer a practical solution to 3D dose verification for conventional radiotherapy as well as intensity-modulated and stereotactic radiotherapy. In this study, EGSnrc calculated and PAGAT polymer gel dosimeter measured dose profiles from single shot irradiation with 18 mm collimator of Gamma Knife in homogeneous and inhomogeneous phantoms were compared with eac...

ID: 5462 Title: Advances in Co-60 based Tomotherapy Including Megavoltage CT Purpose: To evaluate the potential for Co-60 based tomotherapy including dose delivery and mega-voltage CT (MVCT). Tomotherapy is a rotational implementation of IMRT that provides highly conformal doses and patient setup verification using MVCT. Current tomotherapy is limited to linear accelerators. This poster present...

BACKGROUND Radiation-sensitive polymer gels are among the most promising three-dimensional dose verification tools and tissue-like phantom developed to date. OBJECTIVE The aim of this study is an investigating of percentage depth dose enhancement within the gel medium with used of conformal distribution gold nanoparticle as contrast agents by high atomic number material. METHODS In this wor...