A 2-year-old male hamster was presented because of left facial swelling and salivation. Necropsy wasperformed and affected cheek pouch with tissue samples of regional and internal organs were submitted forhistopathological study. In histopathological examination it was found that the tumor consisted of cords andislands of tumoric epithelial cells which were diffused in the dermis. Vacoulation o...

Objective: To examine the role of tartrate resistant acid phosphatase (TRAP) positive mononuclear and multinucleated cells in the destruction of articular cartilage in patients with rheumatoid arthritis (RA). Methods: The presence of TRAP positive cells in the synovial tissue of patients with RA was examined by enzyme histochemistry and immunohistochemistry. Expression of mRNAs for matrix metal...

Introduction . Psoriatic disease is a heterogeneous inflammatory with different clinical manifestations, including plaque psoriasis and psoriatic arthritis. It has been shown that elevated levels of TNF- α are observed in both arthritis psoriasis. Studying the gene expression pattern can help differential diagnosis between The objective to study blood mononuclear cells patients for possible the...

Objective: The aim of this study is to observe the homing and distribution of the foreign multidrug resistance gene 1 (mdr1) in gene therapy. Method: After the bone marrow mononuclear cells of male BABL/C which was transferred with retrovirus-mediated mdr1 were transplanted into female Babl/c which was conducted radiotherapy with 60Co-γ, the expression and distribution of foreign mdr1 in the bo...

Intestinal epithelial and mononuclear cells were isolated from normal colonic mucosa and from intestinal mucosa of inflammatory bowel disease patients. Prostanoid synthesis by primary cultures of intestinal mononuclear cells were four to six fold higher than its synthesis by primary cultures of epithelial cells. Prostaglandin E2, prostacyclin and thromboxane A2 synthesis by cultured mononuclear...

The effects of mononuclear cells from nontransfused and transfused dogs on the growth of erythroid colonies (EC) from DLA-identical littermates were studied. To this purpose, marrow samples were cultured both before and after one to three transfusions from the DLA-identical littermate. Mononuclear cells obtained before transfusions and cocultured with autologous marrow or marrow from DLAidentic...

OBJECTIVES Severe intervertebral disc herniation causes complete paraplegia and loss of pain sensation in canines. The prognosis is poor, even when decompression surgery is performed immediately after onset. Studies suggest that bone marrow-derived mononuclear cells will regenerate the injured spinal cord and restore neurologic function. This study was conducted to assess the clinical efficacy ...

OBJECTIVES Immune recognition of the major structural proteins of rubella virus by peripheral blood mononuclear cells and synovial inflammatory infiltrates of a patient with documented chronic rubella associated arthritis was compared with responses of normal healthy rubella virus immunoreactive subjects to establish if there were unusual response patterns associated with rubella associated art...

Purpose: Mammalian target of rapamycin (mTOR)is important in hematopoiesis and affect cell growth,differentiation and survival. Although previous studies were identified the effect of cytokines on the mononuclear cells development however the cytokines effect on mTOR in cord blood mononuclear cells was unclear. The aim of this study was to evaluate mTOR expression in cord blood mononuclear and ...