Controlled osmotic lysis (water-washing) of rat liver mitochondria results in a mixed population of small vesicles derived mainly from the outer mitochondrial membrane and of larger bodies containing a few cristae derived from the inner membrane. These elements have been separated on Ficoll and sucrose gradients. The small vesicles were rich in monoamine oxidase, and the large bodies were rich ...

Monoamine oxidase (MAO) is an enzyme that metabolizes monoamines, and are also vital to

Monoamine oxidase (MAO) is an enzyme that metabolizes monoamines, and are also vital to

Reaction-based fluorescent probes for monoamine oxidases A and B are developed based on a new two-photon absorbing compound and its precursor. The probes show turn-on fluorescence response to the enzymes owing to the two-photon absorbing compound produced by the enzymatic activity, as monitored by one- as well as two-photon microscopy for the first time.

In the present study, nine compounds (1-9) were isolated from Talaromyces wortmannii LGT-4 (anendophytic fungus from Tripterygium wilfordi) which was cultured in CYM Medium. Their structures were determined as 4-hydroxyphthalide (1), Fumitremorgin C (2), Ergosterol (3), 3-(2-hydroxypropyl)-8-h...

MAN MAO-QIANG, KENNETH R. FEINGOLD, FUSHENG WANG, CARL R. THORNFELDT, and PETER M. ELIAS, Dermatology and Medicine Services, Veterans Administration Medical Center, San Francisco, CA 94121 (M.M-Q., K.R.F., P.M.E.); Departments of Dermatology (M.M-Q., K.R.F., P. M. E. ) and Medicine (t•. if. t • . ), University of California School of Medicine, San Francisco, CA; Department ofDermatology, Yuhuan...