In view of the call by the World Health Organization (WHO) for elimination of schistosomiasis as a public health problem by 2025, use of molluscicides in snail control to supplement chemotherapy-based control efforts is likely to increase in the coming years. The mechanisms of action of niclosamide, the active ingredient in the most widely used molluscicides, remain largely unknown. A better un...

although this practice is not effective. Snails and slugs withdrew from produce after the molluscicide was applied to surrounding vegetation, but returned after several days. We purchased a lettuce head that had been reportedly treated with molluscicides at the Coronation Market and found a small slug inside. The role of produce in transmitting A. cantonensis is still unclear; humans may become...

The aim of the present study was to observe the effect of seasonal variations (abiotic factors) on the toxicity of carbaryl to L. acuminata. In each month during the year 2006-2007, the 24h LC50 values of the molluscicide carbaryl were determined in an out-door study with the snail Lymnaea acuminata, with concomitant estimation of levels of abiotic factors viz., temperature, pH, dissolved oxyge...

The genetic and embryotoxic effects of bis(tri-n-butyltin)oxide (TBTO) were evaluated in multiple in vivo and in vitro short-term tests preparatory to its potential wide use as a molluscicide in control of schistosomiasis. When tested in the rec assay in Bacillus subtilis, TBTO was not mutagenic and it did not induce reverse mutations in Klebsiella pneumoniae. Neither in the presence nor in the...

BACKGROUND Schistosomiasis remains a major public health concern in China. Since 2004, an integrated strategy was developed to control the transmission of Schistosoma japonicum in China. However, the long-term effectiveness of this integrated strategy for the interruption of schistosomiasis transmission remains unknown in the mountainous and hilly regions of China until now. This longitudinal s...

Natural products play an important role in drug discovery and many approved therapeutics as well as drug candidates have been derived from natural sources. They have been the source of most of the active ingredients of medicines. The beneficial medicinal effects of plant materials typically result from the combinations of secondary products present in the plan. These secondary metabolites const...

Ended is the Ethiopian name for Phytolacca dodecandra, a full shrub closely related to the American pokeweed, Phytolacca americana. The young green leaves and shoots are edible protein sources after they are boiled and the water is discarded. An extract of saponin from P. dodecandra berries can be used as a molluscicide in the control of schistosomiasis and other snail-borne diseases. The berri...

The epidemiology and control of schistosomiasis mansoni in the Municipality of Pedro de Toledo (State of S. Paulo, Brazil) since 1980, has been studied. In 1980 the prevalence evaluated by stool exams (Kato-Katz method) was 22.8% and no statistical difference at 5.0% level was observed between rural and urban zones. The intensity of infection was low (58.5 eggs/g of faeces); the highest prevale...