نتایج جستجو برای: modifying therapies

تعداد نتایج: 132966  

Journal: :P & T : a peer-reviewed journal for formulary management 2014
Susan Worley

Developing a disease-modifying treatment for Alzheimer's disease has stymied researchers. A collaborative re-examination of premises that guided disappointing earlier trials is under way, with talk of new targets and combination therapies.

2011
Richard Nicholas Paolo Giannetti Ali Alsanousi Tim Friede Paolo A Muraro

The emergence of oral disease-modifying therapies in multiple sclerosis (MS) will have a significant impact on the evolving scenario of immunomodulatory treatments in MS where current therapies are all injectable. Reducing relapses in trials translates for individuals with MS into a therapeutic aim of stopping future events. Thus the possible absence of any perceived benefits to the individual ...

2012
Robert J Fox Alan Thompson David Baker Peer Baneke Doug Brown Paul Browne Dhia Chandraratna Olga Ciccarelli Timothy Coetzee Giancarlo Comi Anthony Feinstein Raj Kapoor Karen Lee Marco Salvetti Kersten Sharrock Ahmed Toosy Paola Zaratin Kim Zuidwijk

Despite significant progress in the development of therapies for relapsing MS, progressive MS remains comparatively disappointing. Our objective, in this paper, is to review the current challenges in developing therapies for progressive MS and identify key priority areas for research. A collaborative was convened by volunteer and staff leaders from several MS societies with the mission to exped...

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