Tumor-targeting multifunctional liposomes simultaneously loaded with magnetic iron oxide nanoparticles (MIONs) as a magnetic resonance imaging (MRI) contrast agent and anticancer drug, mitoxantrone (Mit), were developed for targeted cancer therapy and ultrasensitive MRI. The gonadorelin-functionalized MION/Mit-loaded liposome (Mit-GML) showed significantly increased uptake in luteinizing hormon...

Helicobacter sp. MIT 01-6451 has been detected in SPF mice kept in Japan. To characterize strain MIT 01-6451, its infection route during fetal and neonatal life and effects on pregnancy were investigated using immunocompetent and immunodeficient mouse strains (BALB/c, C57BL/6, and SCID). MIT 01-6451 was detected in the uterus, vagina, and mammary glands of 50% of infected SCID mice, whereas the...

In spite of the usual combination form of methotrexate (MTX)/mitoxantrone (MIT) and various complex combination regimens of MTX/MIT with other anticancer drugs, the survival period, cure rate, and systemic toxicity still need to be improved. For this purpose, a nanostructured amino group-modified mesoporous silica nanoparticles (MSNN)-MTX/MIT was designed. In the preparation, the surface of mes...

Hadacidin 2 und seine Monoalkalisalze 3 wurden nach Literaturangaben dargestellt. Das nach 1. c. 1 gewonnene Produkt muß jedoch durch Extraktion mit siedendem Äther und nachfolgende Umfällung mit Chloroform/Petroläther (1 : 4) aus Acetonlösung gereinigt werden. Die IR-Spektren wurden mit Infrarotspektrometern IR-10 (4000 — 300 c m 1 , KBr-Preßlinge) und IR-11 (700 — 33 c m 1 , Nujolaufschlämmun...

Field: Physics Article Title: Vortices and superfluidity in a strongly interacting Fermi gas Authors: Zwierlein, MW;Abo-Shaeer, JR;Schirotzek, A;Schunck, CH;Ketterle, W Journal: NATURE Volume: 435 Issue: 7045 Page: 1047-1051 Year: JUN 23 2005 * MIT, Dept Phys, MIT HArvard Ctr Ultracold Atoms, Cambridge, MA 02139 USA. * MIT, Dept Phys, MIT HArvard Ctr Ultracold Atoms, Cambridge, MA 02139 USA. * ...

Changing Paths: The Impact of Manufacturing Offshore on Technology Development Incentives in the Optoelectronics Industry Erica R. H. Fuchs Engineering Systems Division, Massachusetts Institute of Technology, Cambridge, MA 02139, [email protected] Randolph E. Kirchain Department of Materials Science and Engineering and Engineering Systems Division, Massachusetts Institute of Technology, Cambridge, M...

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Karthik Shekhar, 2 Claire F. Ruberman, Andrew L. Ferguson, John P. Barton, 2 Mehran Kardar, ∗ and Arup K. Chakraborty 5, 6, 7, 8, † Department of Chemical Engineering, MIT, Cambridge, MA 02139 Ragon Institute of MGH, MIT and Harvard, Boston, MA 02129 Department of Mathematics, Pomona College, Claremont, CA 91711 Department of Materials Science and Engineering, University of Illinois at Urbana-C...

A mixing rule for the mixtures of hard-spheres is presented which can be reduced to the standard van der Waals mixing rule at low densities. The effectiveness of the mixing rule for the size and energy parameters of lennard-Jones fluid are examined by combining them with an equation of state to calculate thermodynamic properties. The results of calculation are compared with the molecular dy...