888 www.thelancet.com Vol 373 March 14, 2009 There is no question that Lorenzo Odone lived until the age of 30 years because his parents, Augusto and Michaela Odone, defi ed doctors and developed a mixture of two cooking oils as a possible treatment for their son’s devastating disease. The 1992 fi lm Lorenzo’s Oil, which commemorated this heroic eff ort, became an inspirational saga for other p...