A graph G is loosely-c-connected, or l-c-connected, if there exists a number d depending on G such that the deletion of fewer than c vertices from G leaves precisely one infinite component and a graph containing at most d vertices. In this paper, we give the structure of a set of l-c-connected infinite graphs that form an unavoidable set among the topological minors of l-c-connected infinite gr...

introduction: the current study evaluated the value of red blood cell (rbc) indices and the corresponding cut- off points for β-thalassemia control programs in iran. materials and methods: 1,150 individuals (575 couples) with low rbc indices and normal hemoglobin a2 who had been referred to the genetic centre of isfahan, were tested during pre-marital screening analyses, in the 2 year period, 2...

A series of symmetrical dimeric proton pump inhibitor (PPI) analogues, designed as novel type DNA minor groove binders, was synthesized and evaluated for anti-tumor activity. Some of these new compounds showed IC(50) values below 10 microM in an in vitro anti-tumor test. A molecular modeling study was performed to confirm the sequence selectivity of these compounds towards AT base pairs in DNA....

BACKGROUND Minor surgery is a well-established part of family practice, but its safety and cost-effectiveness have been called into question. AIM To audit the performance of GP minor surgeons in three different settings. DESIGN AND SETTING A community-based surgery audit of GP minor surgery cases and outcomes from three settings: GPs who carried out minor surgery in their practice funded as...

The crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex...