Silver nanoparticles (AgNP) were synthesized by electrochemical method using high purity metallic silver in the presence of the surfactant Pluronic® f127. The synthesized nanoparticles were characterized using UV-Vis spectroscopy, Dynamic Light Scattering (DLS), X-Ray Dispersion Spectroscopy (XDS) and Scanning Electron Microscopy (SEM). The antimicrobial activity of AgNP was evaluated against E...

The antifungal activities of fluconazole, itraconazole, ketoconazole, terbinafine and griseofulvin were tested by broth microdilution technique, against 60 dermatophytes isolated from nail or skin specimens from Goiania city patients, Brazil. In this study, the microtiter plates were incubated at 28 masculineC allowing a reading of the minimal inhibitory concentration (MIC) after four days of i...

We have studied the antimicrobial action of metronidazole against Bacteroides fragilis and Escherichia coli both in pure cultures and in combination. Concentrations of metronidazole above the minimal inhibitory concentration (MIC) produced a marked bactericidal effect on B fragilis at six hours. E coli however showed only a slight and transitory decrease in population when exposed to concentrat...

The in vitro antimicrobial activity of tobramycin and gentamicin was compared against 362 bacterial isolates. The minimal inhibitory concentration (MIC) of tobramycin was fourfold less than the MIC of gentamicin against most of 119 Pseudomonas organisms. Gentamicin and tobramycin had similar in vitro activity against Enterobacteriaceae and Staphylococcus aureus. Proteus rettgeri were commonly r...

More than 20% of the world's biodiversity is located in Brazilian forests and only a few plant extracts have been evaluated for potential antibacterial activity. In the present study, 705 organic and aqueous extracts of plants obtained from different Amazon Rain Forest and Atlantic Forest plants were screened for antibacterial activity at 100 microg/ml, using a microdilution broth assay against...

Bioassay-guided fractionation of the chloroform extract of Byrsonima fagifolia leaves led to the isolation of active antitubercular compounds alkane dotriacontane (Minimal Inhibitory Concentration-MIC, 62.5 μg mL(-1)), triterpenoids as bassic acid (MIC = 2.5 μg mL(-1)), α-amyrin acetate (MIC = 62.5 μg mL(-1)), a mixture of lupeol, α- and β-amyrin (MIC = 31.5 μg mL(-1)) and a mixture of lupeol, ...

The minimal inhibitory concentration (MIC) values of sulfadiazine, penicillin, and rifampin for meningococcal strains isolated from civilians during 1970 were compared. The strains were isolated from various sources and geographical areas and represented several serogroups. The ranges of MIC values were as follows: 0.05 to 20 mg/100 ml for sulfadiazine, 0.01 to 0.4 mug/ml for penicillin, and 0....

OBJECTIVE The objective of this study was to evaluate whether the outcomes of carbapenem-resistant Acinetobacter infections treated with ampicillin/sulbactam were associated with the in vitro susceptibility profiles. METHODS Twenty-two infections were treated with ampicillin/sulbactam. The median treatment duration was 14 days (range: 3-19 days), and the median daily dose was 9 g (range: 1.5-...

The objective of this study is to determine the tyrosinase inhibition and antibacterial activities against the pathogenic bacteria in the oral cavity of the mangosteen pericarp extract. The results showed that the mangosteen pericarp extract inhibited the tyrosinase enzyme at IC50 = 67 ng/ml. Furthermore, the mangosteen pericarp extract also exhibited the antibacterial activities against the pa...