The chromium of most chromium compounds exists in the form of triand hexa-valences. Application of a chemical method of determination of the former is difficult because the former is far more inactive than the latter. For example, neither an extraction method by organic solvents or a colorimetric method with diphenylcarbazide is suitable to determine Cr+3, because Cr+3 does not react with diphe...

Toxic methemoglobinemia is an uncommon blood disorder induced by exposure to certain oxidizing agents and drugs. In severe cases, this condition may rapidly lead to major cardiopulmonary compromise and constitutes an emergency requiring prompt recognition and early management. We report an unusual case of severe toxic methemoglobinemia following wide cutaneous application of a pomade containing...

Thioredoxin reductase (TrxR) is a central component in the thioredoxin system by involving catalyzing reduction of thioredoxin, which critical for organism survival. Because this essential, it promising target novel antimicrobial agents. Herein, we solved 1.9 Å high‐resolution structure TrxR from Acinetobacter baumannii ( Ab TrxR), Gram‐negative, pathogenic bacterium and drug‐resistant superbug...

Anaerobic dissimilatory ferric iron-reducing and ferrous iron-oxidizing bacteria gain energy through reduction or oxidation of iron minerals and presumably play an important role in catalyzing iron transformations in anoxic environments. Numerous ferric iron-reducing bacteria have been isolated from a great diversity of anoxic environments, including sediments, soils, deep terrestrial subsurfac...

This study describes the organic synthesis of 5-(2-amimo-4-styryl pyrimidine-4-yl)-4-methoxy benzofuran-6-ol (SPBF) as an example of a benzofuran derivative used as a new series of amyloid imaging agents. These benzofuran derivatives may be useful amyloid imaging agents for detecting B-amyloid plagues in the brain of Alzheimer’s disease. The precursor is 1-[6-hydroxy-4-methoxybenzofuran-5-yl]-p...