نتایج جستجو برای: mild cerebral hypoperfusion

تعداد نتایج: 296125  

Journal: :Annals of nuclear medicine 2007
Hiroki Sasaki Kazunari Ishii Atsushi K Kono Naokazu Miyamoto Tetsuya Fukuda Kenichi Shimada Shingo Ohkawa Tetsuro Kawaguchi Etsuro Mori

OBJECTIVES To investigate the specific pattern of cerebral blood flow (CBF) in subjects with idiopathic normal pressure hydrocephalus (iNPH) using voxel-based analysis. METHODS N-isopropyl-p-[123I]iodoamphetamine (IMP) single photon emission computed tomography (SPECT) images were performed in 30 iNPH patients, who met probable iNPH criteria, 30 Alzheimer disease (AD) patients and 15 normal c...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2011
Michell M Reimer Jamie McQueen Luke Searcy Gillian Scullion Barbara Zonta Anne Desmazieres Philip R Holland Jessica Smith Catherine Gliddon Emma R Wood Pawel Herzyk Peter J Brophy James McCulloch Karen Horsburgh

Myelinated axons have a distinct protein architecture essential for action potential propagation, neuronal communication, and maintaining cognitive function. Damage to myelinated axons, associated with cerebral hypoperfusion, contributes to age-related cognitive decline. We sought to determine early alterations in the protein architecture of myelinated axons and potential mechanisms after hypop...

Journal: :Investigative ophthalmology & visual science 2010
Matthew C Holman Glyn Chidlow John P M Wood Robert J Casson

Purpose. Because of differences in energy metabolism between the brain and retina, the hypothesis for the study was that, in a model of ocular and cerebral hypoperfusion, the retina would be protected by short-term hyperglycemia, whereas brain injury would be exacerbated. Methods. Hyperglycemia was induced by intraperitoneal streptozotocin. An initial experiment determined the effect of hypergl...

2017
Manabu Nakagawa Tatsushi Mutoh Shunsuke Takenaka Tomoko Mutoh Tomoko Totsune Yasuyuki Taki Tatsuya Ishikawa

BACKGROUND Delayed cerebral ischemia (DCI) is one of the main causes of poor outcomes after subarachnoid hemorrhage (SAH). The early identification of DCI by noninvasive imaging modalities would provide valuable information of therapeutic intervention for improving the patient outcomes. We aimed to describe the clinical features of cerebral blood flow (CBF) data obtained from the single-photon ...

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