نتایج جستجو برای: microrna 370
تعداد نتایج: 44651 فیلتر نتایج به سال:
bladder cancer is the fifth most common cancer with significant morbidity and mortality. recently, numerous studies demonstrated that micrornas are emerging as diagnostic biomarkers for bladder cancer. specific mirna profiles have been identified for several samples from patients with bladder cancer. micrornas are noncoding rna molecules of approximately 23 nucleotides that play important roles...
objective(s): menopause and diabetes obviously increase the risk of cardiovascular disease in women. the aims of the present study were to evaluate the effects of ovariectomy in type 2 diabetes on the histology and expression of mirna-29, mirna-133, igf-1 and bcl-2 genes and bcl-2 protein and caspase 3 activity in the hearts of female rats. materials and methods: forty female wistar rats were d...
results treatments through mirnas can prove to be beneficial due to its small size, easy synthesis, targeted and quick delivery. conclusions further work is needed to be done to make mirna treatments available to large number of people suffering from various bone diseases. context mirnas can regulate the expression of genes by interfering in their mrnas, acting as key regulators of diverse cell...
The effects of herbivorous zooplankton on the sedimentation of particles out of the euphotic zone are examined with mathematical models, a large-scale field experiment, and descriptive data from a eutrophic lake. The theory is rooted in the population dynamics of phytoplankton and zooplankton and so explicitly accounts for the potential effect of zooplankton grazing on primary production and th...
گاز خردل (سولفور موستارد) از گروه سلاحهای شیمیایی تاول زا است. علیرغم دانش کافی در مورد آثار پاتولوژیک ناشی از مواجهه با گاز خردل، مکانیسم دقیق مولکولی عملکرد این گاز هنوز به درستی مشخص نیست. micrornaها مولکولهای rnaی غیر کدکننده ای هستند که بسیاری از مسیرهای مهم سلولی را تنظیم می نمایند. در این مطالعه، پروفایل بیانی 739 microrna، در نمونه ی سرم 43 مصدوم شیمیایی و 27 نمونه کنترل تعیین شد. آنالی...
Although myocardial ischemia-reperfusion injury (I/R) and its pathological consequences are the leading cause of morbidity mortality worldwide, cardioprotective therapeutics still not on market. Oxidative stress, a major contributing factor to I/R, changes transcription coding non-coding RNAs, alters post-transcriptional modulations, regulate protein function. MicroRNA (miRNA) expression can be...
Alonso, C.R. (2012) A complex ‘mRNA degradation code’ controls gene expression during animal development. Trends in Genetics, 28, 7888. Alvarez‐Saavedra, M., Antoun, G., Yanagiya, A., et al. (2010) miRNA‐132 orchestrates chromatin remodeling and translational control of the circadian clock. Human Molecular Genetics, 20, 731–751. [A very elegant study describing coordinated regulation of epigene...
A desktop computer with System/370 capability was produced by enhancing the IBM Personal Computer XT with additional hardware and developing software that provides a compatible interface. The computer, the IBM Personal Computer XT/370, and this software allow users to run most System/370 Conversational Monitor System application programs unaltered in a desk-top environment. The evolution of the...
Novel species of fungi described in the present study include the following from Malaysia: Castanediella eucalypti from Eucalyptus pellita, Codinaea acacia from Acacia mangium, Emarcea eucalyptigena from Eucalyptus brassiana, Myrtapenidiella eucalyptorum from Eucalyptus pellita, Pilidiella eucalyptigena from Eucalyptus brassiana and Strelitziana malaysiana from Acacia mangium. Furthermore, Stac...
objective(s):micrornas (mirnas) are small non-coding rna molecules that regulate gene expression. they have important roles in kidney development, homeostasis and disease, and participate in the onset and progression of tubulointerstitial sclerosis and end-stage glomerular lesions that occur in various forms of chronic kidney disease (ckd). in the present study, we elucidated the role of micror...
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