نتایج جستجو برای: microrna 23b
تعداد نتایج: 37676 فیلتر نتایج به سال:
To investigate the effect of long non coding RNA MAGI2-antisense 3 on proliferation, invasion and migration cervical cancer cells underlying mechanism. SiHa were divided into plasmid cloning DNA group, DNA-MAGI2-antisense anti-microRNA-negative control anti-microRNA-31-5p 3+microRNAnegative group 3+microRNA-31-5p group; quantitative reverse transcription polymerase chain reaction was used to de...
Long noncoding RNAs (lncRNAs) have been reported to play critical role in the development of diabetic nephropathy (DN). However, effects and mechanism plasmacytoma variant translocation 1 (PVT1) remain poorly understood. The expression PVT1, miR-23b-3p, early growth response factor (EGR1), Fibronectin (FN), Collagen IV (Col IV), alpha smooth muscle actin (α-SMA), E-cadherin, vimentin, transform...
Microvesicles (MVs) are 30-1,000-nm extracellular vesicles that are released from a multitude of cell types and perform diverse cellular functions, including intercellular communication, antigen presentation, and transfer of proteins, messenger RNA and microRNA (also known as miR). MicroRNAs have been demonstrated to be aberrantly expressed in leukemia, and the overall microRNA expression profi...
Growth of atherosclerotic plaque requires neovascularization (angiogenesis). To elucidate the involvement of angiotensin II (Ang II) in angiogenesis, we performed gene microarray and microRNA (miRNA) polymerase chain reaction array analyses on human coronary artery endothelial cells exposed to moderate concentration of Ang II for 2 and 12 hours. At 12, but not 2, hours, cultures treated with An...
Herein, we aimed at identifying global transcriptome microRNA (miRNA) changes and miRNA target genes in lung adenocarcinoma. Samples were selected as training (N = 24) and independent validation (N = 34) sets. Tissues were microdissected to obtain >90% tumor or normal lung cells, subjected to miRNA transcriptome sequencing and TaqMan quantitative PCR validation. We further integrated our data w...
It is reported that different microRNA (miRNA) profiles can be detected in the blood of cancer patients. We investigated that whether the key serum miRNAs could discriminate patients with and without breast cancer. This study was divided into three parts: (1) miRNA marker discovery using SOLiD sequencing-based miRNA profiling on cancerous and adjacent noncancerous breast tissue of one breast ca...
مقدمه و هدف: سرطان ریه اولین عامل مرگ و میر ناشی از سرطان در جهان است، از این رو تحقیقات زیادی با هدف شناخت مسیرهای درگیر در بیماری در حال انجام است. microrna ها، rna های غیر کدکننده¬ای هستند که در تنظیم بیان ژن نقش دارند. بر هم خوردن تنظیم بیان microrna ها با سرطان¬های مختلفی در ارتباط است. mir-491 در ناحیه¬ی ژنومی 9p21.3 قرار گرفته است. mir-491 از طریق هدف قرار دادن bcl-xl بر مسیر مرگ سلولی ا...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید