نتایج جستجو برای: microrna 21

تعداد نتایج: 283430  

Journal: :Biosensors & bioelectronics 2014
Mo Wang Huanshun Yin Nannan Shen Zhenning Xu Bing Sun Shiyun Ai

In this work, a photoelectrochemical (PEC) biosensor was fabricated for sensitive and specific detection of microRNA based on Bi2S3 nanorods and enzymatic signal amplification. Using the catalytic effect of alkaline phosphatase on l-ascorbic acid 2-phosphate trisodium salt (AAP), ascorbic acid (AA) was in situ generated and used as electron donor. Based on this, a signal-on protocol was success...

Journal: :Chemical communications 2015
Xiang-Guo Li Anne Roivainen Jörgen Bergman Arttu Heinonen Frank Bengel Thomas Thum Juhani Knuuti

A bicyclononyne-based prosthetic group has been developed for (18)F-labeling of anti-microRNA-21, an oligonucleotide, in a near-stoichiometric manner.

Journal: :basic and clinical neuroscience 0
hossein mostafavi zanjan, iran mojtaba khaksarian khorramabad, iran mohammad taghi joghataei tehran, iran sadegh yoosefee tehran, iran mahmoud reza hadjighassem tehran, iran maryam soleimannejad

introduction: malignant astrocytic gliomas are the most common and lethal brain malignancies due to their refractory to the current therapies. nowadays, molecular targeted therapy has attracted great attention in treatment of glioma. connexin 43 (cx43) and micro ribonucleic acid- 21(mir-21) are among molecules that are involved in glioma development and progression. these molecules showed poten...

Journal: :Circulation 2011
Shijun Hu Mei Huang Patricia K Nguyen Yongquan Gong Zongjin Li Fangjun Jia Feng Lan Junwei Liu Divya Nag Robert C Robbins Joseph C Wu

BACKGROUND Although stem cell therapy has provided a promising treatment for myocardial infarction, the low survival of the transplanted cells in the infarcted myocardium is possibly a primary reason for failure of long-term improvement. Therefore, the development of novel prosurvival strategies to boost stem cell survival will be of significant benefit to this field. METHODS AND RESULTS Card...

2013
S Simbo A Roque-Andrade B Lockard C Baetge S Mertens-Talcott C Rasmussen R Kreider

Background Obesity has been associated with inflammation. However, the mechanisms are not well understood. The purpose of this study was to determine if exercise and diet-induced weight loss would affect markers of inflammation via the Phosphatase and Tensin homologue Deleted from Chromosome-10 (PTEN), TNF receptor-associated factor 6 (TRAF6), Phosphatidylinositol-3-kinase (PI3k), Protein Kinas...

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