The rheological regulation of the “three high” (high temperature, high density and high salinity) water-based drilling fluid is a worldwide problem due to the combined influence of temperature, solid content and salinity. This paper investigates the factors and regulation methods about rheological property of “three high” water based drilling fluid, and the effects of clay, salinity and weighti...

A series of placebo powders for inhalation was characterized regarding bulk density and powder flowability using different techniques. The powders were of the ordered mixture type and were prepared by mixing a pharmaceutical carrier grade of lactose with different fractions of intermediate sized and fine (i.e., micronized) lactose. A modified Hausner Ratio was obtained by measurement of the pou...

A novel extension to a previous method has been proposed to evaluate the nature of dry powder mixing processes using a mixing sensitive colouring agent. The method proposed measures the change in the colour (hue) and colour intensity of the powder blends over mixing time. To evaluate the extent of fine particle dispersion and de-agglomeration, cohesive and free flowing lactose (white) and cohes...

OBJECTIVES To determine the effect of estrogen (E) alone (without the influence of testosterone (T)) on cognitive function in older men, using 17-beta micronized estradiol versus placebo in older men rendered hypogonadal (low T and E) by treatment for prostate cancer. DESIGN Short-term double-blind, randomized, controlled trial. SETTING An outpatient General Clinical Research Center. PART...