Center for bioelectronics, biosensors and biochips http://www.clemson.edu/c3b/projects.html This site describes research being conducted at the Center for Bioelectronics, Biosensors and Biochips at Clemson University. What are biosensors? http://www.lsbu.ac.uk/biology/enztech/biosensors.html This website provides excellent fundamental information on what constitutes a biosensor, their types and...

The development of biochips is a major thrust of the rapidly growing biotechnology industry. Research on biomedical or biochemical analysis miniaturization and integration has made explosive progress by using biochips recently. For example, capillary electrophoresis (CE), sample preconcentration, genomic DNA extraction, and DNA hybridization have been successfully miniaturized and operated in a...

Biochips are engineered substrates that have different spots change colour according to biochemical reactions. These can be read together detect analytes (such as types of antibiotic, pathogens, or biological agents). While some chips designed so each spot on its own a particular analyte, chip designs use combination more efficient and larger number with smaller spots. can, however, difficult d...

Lab-on-a-chip biological platforms have been intensively developed during the last decade since emerging technologies have offered possibilities to manufacture reliable devices with increased spatial resolution and 3D configurations. These biochips permit testing chemical reactions with nanoliter volumes, enhanced sensitivity in analysis and reduced consumption of reagents. Due to the high peak...

This paper presents an integrated offline testing of Single-Fault detection technique for themicro-fluidic based biochips and also diagnosis single defects in order to achieve higherthroughput and less time complexity of the execution process. In the field operation, this is to be used to increase chip dependability and reusability of the biochips. In this paper, a pipelined technique is presen...

A major limitation to using mammalian cell-based biosensors for field testing of drinking water samples is the difficulty of maintaining cell viability and sterility without an on-site cell culture facility. This paper describes a portable automated bench-top mammalian cell-based toxicity sensor that incorporates enclosed fluidic biochips containing endothelial cells monitored by Electric Cell-...

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Membrane-bound proteins represent the single most important class of drug targets. This article discusses the issues surrounding fabrication of membrane-protein microarrays by conventional robotic pin printing techniques. Ligand binding selectivity and specificity to G protein-coupled receptor (GPCR) microarrays are presented. The potential applications of these arrays for drug screening are di...