In this second of two articles, we show that several supercritical processes have been developed to prepare composite particles of poorly soluble active ingredients. Microencapsulation, cyclodextrin inclusion and impregnation allow to incorporate poorly soluble materials in fast-dissolving hydrophilic excipients, leading to promising results in terms of dissolution rate enhancement.

saffron is an important spice values for its color, aroma and flavor in the food industry. a significant proportion of saffron compound is lost during processing and storage because of its volatility and sensitivity to oxidation. thepresent research microencapsulated saffron color compounds (crocin) by freeze drying. the freeze-dried aqueous saffron effective compound extract was first prepared...

Warfarin, zinc phosphide, norbormide and alphachloralose have been microencapsulated by the technique of coacervation and fed to laboratory rats (R. norvegicus) and mice (M. musculus). Results are given of experiments in which the concentration of rodenticide, wall material and phase ratio have been varied separately and in combination. Experiments are also reported in which normal and encapsul...

Essential oil of Citrus family plant is known to have repellent effect against mosquito. Unfortunately, due to its high volatility effect, its repellency effect was compromised. The incorporation of essential oil in a microencapsulation formulation has been shown to help improve the stability and potency of the repellent. In this study, Citrus grandis peel oil (CGPO) was encapsulated by using t...

Essential oil of Citrus family plant is known to have repellent effect against mosquito. Unfortunately, due to its high volatility effect, its repellency effect was compromised. The incorporation of essential oil in a microencapsulation formulation has been shown to help improve the stability and potency of the repellent. In this study, Citrus grandis peel oil (CGPO) was encapsulated by using t...

We present a novel process to encapsulate indocyanine green (ICG) in liposomal droplets at high concentration for potential applications in image-guided drug delivery. The microencapsulation process follows two consecutive steps of droplet formation by liquid-driven coaxial flow focusing (LDCFF) and solvent removal by oil phase dewetting. These biocompatible lipid vesicles may have important ap...