The effect of the surfactant on the size, polydispersity, type of size distribution and structure of nanoparticles synthesized in microemulsions has been studied by computer simulation. The model simulates the surfactant by means of two parameters: the intermicellar exchange parameter, kex, related to dimer life time, and film flexibility parameter, f, related to interdroplet channel size. One ...

The objective was to develop an elemene oil/water (o/w) microemulsion and evaluate its characteristics and oral relative bioavailability in rats. Elemene was used as the oil phase and drug, polysorbate 80 as a surfactant along with ethanol, propylene glycol, and glycerol as the cosurfactants. The microemulsion was prepared by mixing method, or ultrasonication method in an ultrasonic bath. Its t...

The aim of this study is to develop a microemulsion product from a plant essential oil having the highest anti-tyrosinase activity. The in vitro anti-tyrosinase activity of six essential oils extracted from six edible plants was compared. The oil of Cymbopogon citratus demonstrated the highest activity which was significantly nontoxic to normal human cells. The GC-MS data indicated that gerania...

Pd–Co–Au/C catalysts synthesized by the conventional borohydride reduction method and reverse microemulsion method followed by heat treatment at 500–900 C in a reducing atmosphere have been characterized by X-ray diffraction, transmission electron microscopy, and polarization measurements for oxygen reduction reaction (ORR) in proton exchange membrane fuels cells. While a single phase Pd–Co–Au ...

The present paper demonstrates the increased photostability of isotretinoin when loaded in microemulsion. The photodegradation of isotretinoin, in methanol and microemulsion formulation was studied under direct sun light. The photodegradation process was monitored by UV spectrophotometry. In methanol solution, isotretinoin undergoes complete photodegradation just within a few minutes of light e...

We examined the phase behavior of various polyoxyethylene sorbitan fatty acid ester (polysorbates)/ethanol/isopropyl myristate (IPM)/150 mM NaCl solution (NaClaq) systems in order to prepare a microemulsion containing a low ratio of ethanol, which is more suitable for in vivo application. Using polyoxyethylene sorbitan trioleate (Tween 85), which has a large lipophilic moiety, as a surfactant c...

he photon correlation spectroscopy and small-angle X-ray scattering is used for study the mixture of C12E5 microemulsion with PEG in order to determine structure and dynamic of the system. Photon correlation spectroscopy experiment showed an exponential relaxation for pure C12E5 microemulsion that come from Brownian motion of oil nano-droplets in water. The shape of the relaxation changed with ...

ABSTRACT: This research aims to prepare microemulsion from Tea Tree and Rosemary essential oil treat gram-positive gram-negative bacterial infections. A phase titration has been used make the proposed microemulsion, which contained 71% water, 23% of a 1:1 mixture propylene glycol (surfactant), tween 80 (co-surfactant), 6% tea tree/rosemary oil. In pale yellowish transparent droplet size, zeta p...

The available minoxidil formulations for topical application suffer with major drawback and requires repeated application. The present study was aimed to investigate the effect of microemulsions and microemulsion based hydrogel-systems (MEHs) for increased percutaneous penetration of minoxidil. Minoxidil microemulsions were developed by conventional titration method using oleic-acid as oil, twe...