نتایج جستجو برای: micro vessels

تعداد نتایج: 172633  

Journal: :Circulation research 1978
M J Mulvany O K Hansen C Aalkjaer

The mechanical and morphological properties of segments of certain precisely defined resistance vessels (approximately 150 micrometer lumen diameter) in the mesenteric bed of spontaneously hypertensive (SHR) and normotensive (WKY) rats have been compared in vitro under carefully controlled conditions and also after fixation. At a given transmural pressure, the relaxed SHR vessels (compared with...

Journal: :American journal of respiratory cell and molecular biology 2002
Andor R Kranenburg Willem I De Boer J Han J M Van Krieken Wolter J Mooi Jane E Walters Pramod R Saxena Peter J Sterk Hari S Sharma

Important characteristics of chronic obstructive pulmonary disease (COPD) include airway and vascular remodeling, the molecular mechanisms of which are poorly understood. We assessed the role of fibroblast growth factors (FGF) in pulmonary vascular remodeling by examining the expression pattern of FGF-1, FGF-2, and the FGF receptor (FGFR-1) in peripheral area of lung tissues from patients with ...

2016
Saeka Matsuda Masahito Shoumura Naoto Osuga Hidetsugu Tsujigiwa Keisuke Nakano Norimasa Okafuji Takanaga Ochiai Hiromasa Hasegawa Toshiyuki Kawakami

Perforation of floor of the dental pulp is often encountered during root canal treatment in routine clinical practice of dental caries. If perforation were large, granulation tissue would grow to form periodontal polyp. Granulation tissue consists of proliferating cells however their origin is not clear. It was shown that the cells in granulation tissue are mainly from migration of undifferenti...

Journal: :Rheumatology 2013
Guang-Yi Li Yong Feng Tak S Cheng Ji-Min Yin Chang-Qing Zhang

OBJECTIVE To investigate the efficacy of edaravone, a novel free radical scavenger, on preventing steroid-induced osteonecrosis (ON) in a rabbit model. METHODS Thirty-six New Zealand white rabbits were divided into control (C; n = 6), steroid-administered (S; n = 15) and edaravone-administered groups (E; n = 15) after receiving an established protocol of steroid-induced ON. Before and after s...

2017
Nathan Weinstein Luis Mendoza Isidoro Gitler Jaime Klapp

Angiogenesis is an important adaptation mechanism of the blood vessels to the changing requirements of the body during development, aging, and wound healing. Angiogenesis allows existing blood vessels to form new connections or to reabsorb existing ones. Blood vessels are composed of a layer of endothelial cells (ECs) covered by one or more layers of mural cells (smooth muscle cells or pericyte...

Journal: :International journal of epidemiology 2008
Mark Fagan Peter Ball

UK Biobank required a cryogenic facility to store, in vapour phase, a minimum of 5 000 000 1.2 ml capacity micro-tubes held in racks of 96 tubes below -180 degrees C for a 20 year period. The archive would be housed in a 900 m(2) industrial unit remote from the main laboratory area that would be generally unmanned and would require a complete cryogenic infrastructure. A commercial supplier was ...

2016
Ah Young Park Bo Kyoung Seo Sang Hoon Cha Suk Keu Yeom Seung Wha Lee Hwan Hoon Chung

Tumor vascularity is an important indicator for differential diagnosis, tumor growth, and prognosis. Superb micro-vascular imaging (SMI) is an innovative ultrasound technique for vascular examination that uses a multidimensional filter to eliminate clutter and preserve extremely low-velocity flows. Theoretically, SMI could depict more vessels and more detailed vascular morphology, due to the in...

2014
Jirko Kühnisch Jong Seto Claudia Lange Susanne Schrof Sabine Stumpp Karolina Kobus Julia Grohmann Nadine Kossler Peter Varga Monika Osswald Denise Emmerich Sigrid Tinschert Falk Thielemann Georg Duda Wenke Seifert Thaqif el Khassawna David A. Stevenson Florent Elefteriou Uwe Kornak Kay Raum Peter Fratzl Stefan Mundlos Mateusz Kolanczyk

Bone fragility due to osteopenia, osteoporosis or debilitating focal skeletal dysplasias is a frequent observation in the Mendelian disease Neurofibromatosis type 1 (NF1). To determine the mechanisms underlying bone fragility in NF1 we analyzed two conditional mouse models, Nf1Prx1 (limb knock-out) and Nf1Col1 (osteoblast specific knock-out), as well as cortical bone samples from individuals wi...

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