BACKGROUND Reduced growth and osteopenia are common in individuals with cystic fibrosis (CF). Additionally, improved weight and height are associated with better lung function and overall health in the disease. Mechanisms for this reduction in growth are not understood. We utilized a new CFTR knockout rat to evaluate growth in young CF animals, via femur length, microarchitecture of bone and gr...

The addition of malonyldialdehyde (5-20 micro M) to human erythrocytes results in a marked decrease in cellular deformability as measured with a counter-rotating, cone plate Rheoscope when low shear forces (2.5-25 dynes/sq cm) are applied. At high shear forces (125-500 dynes/sq cm), malonyldialdehyde at 5 micro M had no effect on deformability, although at concentrations of 10 and 20 micro M a ...

Solid/liquid interfaces are important locations for various chemical reactions, such as electrode chemical reactions and metal corrosions. Conventional surface analytical methods, such as XPS and SEM-EDS, have been applied to solid materials after being removed from the liquid phase. These methods do not involve direct observation, although useful information is available. It is important to di...

The stainless steel bipolar plate has received much attention due to the cost of graphite bipolar plates. Since the micro-channel of bipolar plates plays the role of fuel flow field, electric connector and fuel sealing, an investigation of the deep drawing process for stainless steel micro-channel arrays is reported in this work. The updated Lagrangian formulation, degenerated shell finite elem...

In this study, a dynamic Mindlin–Reissner-type plate is developed based on simplified version of Mindlin’s form-II first-strain gradient elasticity theory. The governing equations motion and the corresponding boundary conditions are derived using general virtual work variational principle. presented model contains, apart from two classical Lame constants, one additional microstructure material ...

Capacitive Micro-machined Ultrasonic Transducers (CMUTs) are the ultrasonic devices which produce better features in contrast to piezoelectric transducers. The intrinsic parameter of CMUT varies with the variation in geometrical dimension of the device. The cavity height and the radius of the CMUT with circular membrane is varied in the lumped parallel plate model for its impact on the paramete...

Mechanical degradation by shear is one of the mechanisms that limits life-time lubricating grease in a rolling bearing. It results change micro-structure thickener–oil system, leading to bleed and consistency. The resistance can be quantified using worker. In this article, novel approach described, where worker used measure rheological properties situ, while aging grease. energy pressure losses...