BACKGROUND Micro-needles were proposed as one of the alternatives to deliver drugs painlessly passing through stratum corneum in recent years. In this work, a mathematical model is presented to characterize the in fusion flow of a hollow micro-needle array driven by a micro-pump. METHODS By assuming the injection of each micro-needle undergoes a spherical expansion and diffusion, the model is...

We present in this paper a study on the thermal behavior of a square micro coil that will be integrated in a DC-DC micro converter. The first, we calculate the value of inductance. The second, we descript our micro coil; dimensioning, electrical model, and formula of loss. A buck micro converter schematic simulation coupled with ideal and integrated micro coil was presented. This conceptual mod...

3 1 Computational Homogenization Approach Micro-scale Boundary Conditions 32 3 2 Micro-Macro linking Transferring Fluxes and Diffusivities 36 3 3 Micro-scale model 37 3 3 1 Description of flow in the porous matrix at micro-scale 38 3 4 Macro scale model 41 3 5 Tracking of the interface using level set method and adaptive meshing 46 3 6 Computational approach and Numerical Results 47 3 6 1 Conve...

We use micro data on product prices linked to information on the firms that set them to test for selection effects (state dependence) in micro-level producer pricing. In contrast to using synthetic data from a canonical menu-cost model, we find very weak, if any, micro-level selection effects when running price change probability regressions on actual data. Moreover, when fitting a model that n...

Effective elastic properties of a defected solid with distributed cohesive micro-cracks are estimated based on homogenization of the Dugdale–Bilby–Cottrell–Swinden (Dugdale–BCS) type micro-cracks in a two dimensional elastic representative volume element (RVE). Since the cohesive micro-crack model mimics various realistic bond forces at micro-scale, a statistical average of cohesive defects can...

In a two-photon femtosecond laser system of three-dimensional micro-fabrication, a model of micro-device is fabricated layer by layer along its contours of cross-sections. So it is necessary to generate cutting path. In this paper, we present an efficient algorithm to generate cutting path which is a series of ordered contour points on each cross-section of a model. Keyword. Micro-fabrication, ...

Micro learning is gradually becoming a common learning mode in massive open online course learning (MOOC). We illustrate a research strategy to formalize and customize micro learning resources in order to meet personal demands at the real time. This smart micro learning environment can be organized by a Software as a Service (SaaS) we newly designed, in which educational data mining technique i...