نتایج جستجو برای: michigan cancer foundation7 cells
تعداد نتایج: 2102575 فیلتر نتایج به سال:
Abstract Boswellia has been widely used in traditional medicine for the treatment of different diseases such as cancer in Iran. The aim of this study was to evaluate the effect of the gum methanol extract of Boswellia thurifera on the viability and P53 gene expression of cultured breast cancer cells. The gum methanol extract was obtained in various concentrations using the maceration method. No...
Background & Aim: Although studies have shown that ibuprofen has anticancer effects on many cancer cells, the mechanism of the ibuprofen anticancer effect in cancer cells is not still well understood. The aim of this study was to investigate the effect of cytotoxic concentration of ibuprofen on the expression level of MMP-9 and NM23 genes in cervical cancer cells. Materials & Methods: During t...
Stem cells occur in many somatic tissues of multicellular organism and are important participants in their physiology. Stem cells have three distinctive properties: 1- self-renewal, 2- the potential to proliferate extensively and 3- capability to develop into multiple lineages. Every time a stem cell divides, it makes one exact copy and one progenitor cell. Progenitor cells have finite division...
Background & Aims: Lung cancer is the most common cancer in men and the main cause of male cancer deaths worldwide. Also, it is the second leading cause of cancer deaths in women worldwide. In this study, we replaced miRNA145 in lung cancer cells by vector based miRNA-145, then the level of miRNA expression in these cells increased and we investigated the effects of the miRNA on inhibition of m...
Objective(s): Breast cancer remains a global challenge, and further chemopreventive therapies are still immediately required. Emerging evidence has revealed the potent anti-cancer effects of biguanides, Metformin (MET) and phenformin (PHE). Thus, to explore an efficient chemopreventive strategy for breast cancer, the antiproliferative effects of the combination of MET and PHE against breast can...
Background & Aim:Breast cancer is the second most common cancer in women after lung cancer. Given that the herbal ingredients are used for centuries to treat cancer,The aim of this study was to determine the cytotoxic effect of hydroalcholic extract from Thymus daenesisCelak on MCF-7 cancer cells line. Experimental: Breast cancer cells MCF-7 and natur...
Background and Objective: Breast cancer is claimed to be a common cancer amongst women. Estrogen receptors are over-expressed in breast cancer and susceptible to anti-estrogenic effects of tamoxifen. Tamoxifen resistance is a major problem in breast cancer treatment. It has been shown that allicin is an organosulfur compound that is effective in apoptosis induction and cell death in various tum...
objective(s): berberine is one of the main alkaloids and it has been proven to have different pharmacological effects including inhibition of cell cycle and progression of apoptosis in various cancerous cells; however, its effects on cancer metastasis are not well known. cancer cells obtain the ability to change their chemokine system and convert into metastatic cells. in this study, we examine...
Tumor-targeted therapies are playing growing roles in cancer research. The exploitation of these powerful therapeutic modalities largely depends on the discovery of tumor-targeting ligands. Phage display has proven a promising high throughput screening tool for the identification of novel specific peptides with high binding affinity to cancer cells. In the present study, we describe the use of ...
Tumor-targeted therapies are playing growing roles in cancer research. The exploitation of these powerful therapeutic modalities largely depends on the discovery of tumor-targeting ligands. Phage display has proven a promising high throughput screening tool for the identification of novel specific peptides with high binding affinity to cancer cells. In the present study, we describe the use of ...
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