Reaction between aromatic aldehydes and 3–methyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-SiO2/HClO4 in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1H-pyrazol-5-ol derivatives in high yields.

Methyl 9-(1-methyl-1H-indol-3-yl)-9-oxononanoate was synthesized using Friedel–Crafts acylation between N-methyl indole and methyl 9-chloro-9-oxononanoate. The structure of the newly compound elucidated 1H-NMR, 13C-NMR, NOESY-1D, ESI-MS, FT-IR, UV-Vis spectroscopy.

objective: infantile spasm is an age dependent ant myoclonic seizure which occurs in 25 per 100,000 live births. we aimed to investigate effect of intravenous methypredinsolone pulse on the infantile spasm in patients hospitalized in 17 shahrivar hospital, rasht. materials and methods: this is an observational case series which was conducted on 20 infants with infantile spasms hospitalized in 1...

novel citric acid modified starch-carboxy methyl cellulose (cmc) -montmorillonite (mmt) bionanocomposite films were prepared by casting method and the effect of mmt on the structural and physical properties of the starch-cmc biocomposites was studied. x-ray diffraction test showed thatstrong polar interactions between the hydroxyl groups present in the starch and cmc chains and in the silicate ...

rodlet cells are frequently found in teleost fishes and although their role in organisms is not completely understood. the occurrence of these cells are related to stress and may undergo changes in contaminated environments, thereby allowing their use as biomarkers. this hypothesis is tested in the present study. thirty specimens of oreochromis niloticus were divided into three groups, two grou...

a simple, economical, precise and fast visible spectrophotometric method has been developed for the determination of azathioprine in tablet dosage form. developed method is based on the formation of extractable colored complex of drug with colouring agent indigo carmine and methyl orange. a wavelength maximum was found to be 683.7 nm and 566 nm. the concentration range of 15-50 μg ml-1 with of ...

To determine the non-bonded interaction between methyl benzoate and boron nitridenanotube, we focused on an armchair single-wall boron nitride nanotube (9,9) With length 5 angstroms.The geometry of molecules was optimized using B3LYP method with 6-31g* basis set. Also reactivityand stability of methyl benzoate and boron nitride nanotube (9,9) was checked. Then NBO, FREQ,...

reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2- carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)- substituted-quinolines (lo), which were converted to compound 11 with phosphorus oxychloride. substituted-2-(l-methyl-5-nitro-2-imidazo1yl)-4.- methyl-(or phenyl-) quinolines (14) were prepared through the reaction of 2- acetyl-5-nitro-1-methyl-imi...