Összefoglaló. A methaemoglobinaemia az oxigén szállítására képtelen methemoglobin szintjének kóros emelkedését jelenti a vérben, ami jelentős szöveti oxigénhiányt okozhat, súlyos, akár életveszélyes tünetekhez vezethet. Methaemoglobinaemiát számos, oxidáló hatású exogén anyag idézhet elő, ezek közé tartoznak partidrogként használt alkil-nitritek, ún. „popperek” is. „poppereket” korábban „alacso...

Methemoglobinemia is a disorder of the blood caused by abnormally high levels of methemoglobin (MetHb) in the red blood cell (RBC) resulting from simultaneous uptake of oxygen (O2) and nitric oxide (NO) by the human lungs. MetHb is produced in the RBC by irreversible oxidation of the oxygen carrying ferrous ion (Fe) of the heme group of the hemoglobin (Hb) molecule to its nonoxygen binding ferr...

Three patients developed methaemoglobinaemia after eating meat contaminated with excessive nitrites. Diagnosis was delayed in the first two mild cases but was promptly made in the third most severely affected case.

OBJECTIVE To report two cases of methemoglobinemia induced by inhaled nitrobenzene and dermally absorbed aniline. METHODS We have evaluated a 37-year-old male worker exposed to nitrobenzene by inhalation while conducting maintenance job of mononitrobenzene pump and a 25-year-old male worker exposed dermally to aniline while unloading. RESULTS The first case is a 37-year-old male exposed to ...