Background: The fast development of Fourier transform infrared (FTIR) spectroscopy has proposed a novel avenue for distinguishing cancerous tissue from normal one. The aim of this research is to investigate the possibility of employing FTIR spectroscopy with support vector machine (SVM) classification as a new spectral discriminant method for classifying metastatic and non-metastatic lymph node...

Introduction The integrated patient-centered, evidence-based approach to care recognizes the role of patient preferences. A discrete choice experiment (DCE) was developed with aim identifying preferences men prostate cancer in Italy regarding different risk-benefit factors various treatment options. Methods DCE support patients and oncologists based on a targeted scoping review. final included ...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: ca 15.3 is elevated in most patients with distant metastatic breast cancer who had prognostic information. the present study was performed to estimate predictive ability of ca 15.3 in assessment of symptomatic metastasis in patients with breast cancer. materials and methods: during five years, 159 primary breas...

background & objective: abdominal cutaneous and subcutaneous nodules are uncommon lesions which may be benign or malignant. majority of the malignant nodules are metastatic in origin and may be the initial presentation of primary malignancy, hence an early diagnosis is important. our aim was to find out the spectrum of lesions (both non-neoplastic and neoplastic) that present as cutaneous a...

BACKGROUND The prognosis of colorectal cancer patients is to a considerable extent determined by the metastatic potency of the primary tumor. However, despite the fact that liver metastases are the leading cause of death for cancer patients, the molecular basis still remains poorly understood and independent prognostic markers have not been established. MATERIALS AND METHODS Comparative genom...

background: melanoma causes the greatest morbidity and mortality of all skin cancers. mucosal melanoma is a rare but highly aggressive neoplasm. according to previous studies the prevalence of kit mutations in acrallentiginous and mucosal melanomas is relatively low (less than 15–20%), but it can have profound therapeutic implications for localized high risk or metastatic diseases. our goal was...

The relationship between expression of nucleoside diphosphate kinase (NDP kinase)/nm23, c-Ha-ras, and c-myc genes and metastatic potential was assessed in rat-transplantable osteosarcoma lines, derived from spontaneous and chemical carcinogen (4-hydroxyamino quinoline 1-oxide)-induced osteosarcomas in Fischer 344/NS1c rats. These osteosarcomas possess metastatic potential and highly metastatic ...

A special form of prostate cancer is non-metastatic castration-resistant cancer. Patients with this have rising prostate-specific antigen and castrate testosterone levels, no radiological findings metastatic disease on computed tomography bone scan. The phase III trials demonstrated apalutamide, darolutamide or enzalutamide to be associated a significantly longer median metastasis-free survival...