نتایج جستجو برای: merozoite surface protein

تعداد نتایج: 1797353  

Journal: :African health sciences 2012
G I Olasehinde C S Yah R Singh O Olusola Ojuronbge A A Ajayi N Valecha A O Abolaji A O Adeyeba

BACKGROUND Plasmodium falciparum the main causative agent of malaria is an important public health vector. With the use of PCR, its genetic diversity has been extensively studied with dearth information from Nigeria. METHODS In this study, 100 P. falciparum strains merozoite surface protein 1(msp-1), merozoite surface protein 2 (msp-2) and Glutamate rich protein (Glurp) from Ogun State Genera...

Journal: :Infection and immunity 2001
W O Rogers J K Baird A Kumar J A Tine W Weiss J C Aguiar K Gowda R Gwadz S Kumar M Gold S L Hoffman

A nonhuman primate model for malaria vaccine development allowing reliable, stringent sporozoite challenge and evaluation of both cellular and antibody responses is needed. We therefore constructed a multicomponent, multistage DNA vaccine for the simian malaria species Plasmodium knowlesi including two preerythrocytic-stage antigens, the circumsporozoite protein (PkCSP) and sporozoite surface p...

2013
S Josefin Bartholdson Cécile Crosnier Leyla Y Bustamante Julian C Rayner Gavin J Wright

The invasion of host erythrocytes by the parasite Plasmodium falciparum initiates the blood stage of infection responsible for the symptoms of malaria. Invasion involves extracellular protein interactions between host erythrocyte receptors and ligands on the merozoite, the invasive form of the parasite. Despite significant research effort, many merozoite surface ligands have no known erythrocyt...

Journal: :African health sciences 2016
Olatunji Matthew Kolawole Olugbenga Ayodeji Mokuolu Yetunde Adeola Olukosi Tolulope Ololade Oloyede

BACKGROUND Plasmodium falciparum, the most dangerous malaria parasite species to humans remains an important public health concern in Okelele, a rural community in Ilorin, Kwara State, Nigeria. There is however little information about the genetic diversity of Plasmodium falciparum in Nigeria. OBJECTIVE To determine the population genomic diversity of Plasmodium falciparum in malaria patients...

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