The effect of mercury compounds has been tested on the organic cation transporter, hOCTN1. MeHg(+), Hg(2+), or Cd(2+) caused strong inhibition of transport. 1,4-Dithioerythritol (DTE), cysteine (Cys), and N-acetyl-l-cysteine reversed (NAC) the inhibition at different extents. 2-Aminoethyl methanethiosulfonate hydrobromide (MTSEA), a prototype SH reagent, exerted inhibition of transport similar ...

I. Vezér, T., Schulz, H., Nagymajtényi, L.: memory effects following subchronic organic and inorganic lead administration in rats. J. Physiol. (London) 526: 162P-163P (2000) Impact factor: 4,455 II. Vezér, T., Papp, A., Nagymajtényi, L.: Behavioral and neurotoxicological alterations induced by subchronic inorganic lead and mercury treatment in rats. Neurobiology 9: 273 (2001) III. Vezér, T., Pa...

It has been reported that mercury was contained in the tissue of, and eggs laid by hens fed experimentaly seed grains treated with methyl mercury dicyandiamide (1, 2). In the field, it has also been pointed out the remarkably high mercury contents in seed-eating birds, such as pheasants, and predatory animals living on such birds, suggesting that it may be explained by the existence of alkyl me...

Mercury is a metal found in elemental, organic, and inorganic forms in the nature. This substance is present in the composition of earth crust, soil, air, and even in some tissues of plants and sea animals. Each year nearly 3400 tons of mercury compounds are released in the environment, which 95% settle in the soil, 3% in the oceans, and 2% in the atmosphere. Different industrial products li...

Mercury toxicity mediated by different forms of mercury is a major health problem, however, the molecular mechanisms underlying toxicity remains elusive. We analyzed effects of mercuric chloride (HgCl2) and monomethylmercury (MeHg) on the proteins of the mammalian thioredoxin system, thioredoxin reductase (TrxR) and thioredoxin (Trx), and of the glutaredoxin system, glutathione reductase (GR) a...

METHYLATION OF MERCURY BY MICROORGANISMS ..................................... 96 Mechanism of Methylation of Mercury....................................................... 96 Methylmercury Formation Under Anaerobic Conditions ........................................ 97 Methylmercury Formation Under Aerobic Conditions .......................................... 97 Effects of HgS on Methylation o...

BACKGROUND A new organodithiophosphorus derivative, namely O-(1,3-Bispiperidino-2-propyl)-4-methoxy phenyldithiophosphonate, was synthesized and then the kinetic behavior of the transport process as a function of concentration, temperature, stirring rate and solvents was investigated. RESULTS The compound 1 was characterized by elemental analysis, IR, 1H and 31P NMR spectroscopies. The transp...