Evaluation of tear volume is important for diagnosing dry eye disease. At the clinical site, dedicated devices such as slit lamp microscopy or Schirmer’s test strip have been used to quantify tear volume by ophthalmologist. However, these devices have access only in medical office and therefore have limited availability for the public. Tear volume changes with environmental, physical or psychol...

The aim of the current in vitro study was to investigate if tissue surface modification with collagenase and addition of the TGF-β3 can increase the number of cells present in meniscus tears repaired with the use of newly developed tissue adhesives based on isocyanate-terminated block copolymers. Cylindrical explants were harvested from the inner part of bovine menisci. To simulate a full-thick...

BACKGROUND The objective of rehabilitation following meniscal repair is to promote healing by limiting stresses on repairs, while simultaneously preserving muscle strength and joint motion. Both protective protocols limiting weight bearing and accelerated which do not, have shown clinical success. This study assesses the effects of physiologic gait loading on the kinematic behavior of a repaire...

PURPOSE To investigate the incidence of root tears of the posterior horn of the medial meniscus in total knee replacement arthroplasty for knee osteoarthritis and retrospectively analyze clinical results and factors associated with root tears. MATERIALS AND METHODS There were 197 knees of 140 enrolled patients who had undergone total knee replacement arthroplasty between September 2010 and Ma...

The purpose of this study was to document the pattern ligament and meniscal injuries that occur with proximal tibia fractures due high energy trauma. Seventy patients high-energy mechanisms were evaluated magnetic resonance imaging (MRI) knee. All studies reported by a single musculoskeletal radiologist who blinded surgical physical findings. Of 70 patients, there 42 AO/OTA type 41B2 (60%) frac...

We report here on a new arthroscopic direct repair technique for a radial tear of the posterior root of the medial meniscus (PRMM) using a posterior trans-septal portal. Radial tears of the PRMM are commonly observed in the elderly population of Korea and Japan, and the life style of these people requires squatting and kneeling down in daily life. A radial tear of the PRMM results in the loss o...

BACKGROUND Autologous platelet-rich plasma (PRP) has been proven to be very effective on tissue regeneration and wound healing. Here we investigate the potential use of PRP in the treatment of symptomatic dry eye. METHODS Eighteen consecutive patients with symptomatic dry eye were treated with topical PRP and followed up for 1 month. Disappearance of subjective symptoms, increase in best corr...

BACKGROUND In 2002, Moseley et al published a randomized controlled trial (RCT) that showed no difference between knee arthroscopy and placebo for patients with osteoarthritis (OA). We wanted to assess the impact of the trial on clinical practice in the United States. PURPOSE/HYPOTHESIS To evaluate changes in knee arthroscopy practice before and after publication of the article by Moseley et ...

Case Report A sixteen-year-old white girl had a history of pain in the right knee for four months, especially in the medial joint line, and occasional episodes of giving-way during sports activities. She could recall no trauma to the knee. Examination of the knee was unremarkable except for slight tenderness over the medial joint line. There was no effusion, and the McMurray and Lachman tests w...

Abstract— Knee joint is very complex and delicate joint in human body structure. Due to weight load, stress, knees can be injured and damaged and Osteoarthritis (OA) is one of the common diseases of knee injury. It is a degenerative joint disease in which cartilage slowly degrades. Another problem of knee is meniscus tear. Meniscus act as a weight distributer on joint surfaces and gives stabili...