Anthrax is a zoonotic infection which spreads by handling or eating infected product of infected animals and by inhalation of Bacillius anthrax spores (1). Meningoencephalitis is a rare clinical condition of anhtrax which almost has an aggressive clinical course and fatal outcome despite aggressive antibiotic therapy and intensive care supports. Anthrax is diagnosed by detecting B. anthracis in...

The leucocyte adhesion molecule L-selectin (CD62L) is rapidly cleaved off proteolytically after cell activation, generating soluble L-selectin (sCD62L) molecules. sCD62L concentrations were determined in 185 cerebrospinal fluid (CSF) samples obtained from children aged 1 month to 17 years. In 36 CSF samples of children with meningoencephalitis, sCD62L was significantly higher (median 209 fmol/m...

F. Francesconi, MD A.C. Francesconi do Valle, MD, PhD M.T.T. Silva, MD, PhD R.L.B. Costa, MD, MSc E. Carregal, MD S. Talhari, MD, PhD Neurologic manifestations of paracoccidioidomycosis are uncommon. Generally, these are characterized by headache, seizures, or focal neurologic deficits due to a focal brain lesion. We describe a patient with subacute meningoencephalitis, CSF evidence of paracocc...

This paper reports a severe case of eosinophilic meningoencephalitis after infection with Angiostrongylus cantonensis.

The cases are reported of two infants with pneumococcal meningitis in whom initial antibiotic treatment was ineffective despite the organisms being sensitive to the drugs used. A clinical and radiological diagnosis of meningoencephalitis was made. A rapid improvement followed the addition of rifampicin treatment.

We report an 8 month-old infant with primary amebic meningoencephalitis (PAME) due to Naegleria fowleri. The child was treated with amphotericin B, chloramphenicol and rifampicin for 3 weeks. PAME is an almost universally fatal condition with very few survivors till date. Our patient was one of the rare survivors who recovered after treatment and was discharged without any residual neurological...

Streptococcus pneumoniae is a common cause of bacterial meningitis, frequently resulting in severe neurological impairment. A seven-month-old child presenting with Streptococcus pneumoniae meningoencephalitis developed right basal ganglia and hypothalamic infarctions. Daily episodes of agitation, hypertension, tachycardia, diaphoresis, hyperthermia, and decerebrate posturing were observed. The ...

Real-time sonographic findings in 20 infants with bacterial meningitis are reported. The spectrum of features included normal scans, ventricular enlargement, focal areas of increased cortical echogenicity, ventricular bands, and cerebral abscess. Areas of increased cortical echogenicity on sonography representing meningoencephalitis corresponded to areas of contrast enhancement seen on computed...

OBJECTIVE To describe a case with Brucella-associated meningoencephalitis. In addition, we report drug-induced hepatotoxicity due to acyclovir. CLINICAL PRESENTATION AND INTERVENTION A young woman was admitted with fever and psychosis and neuroimaging findings indicative of meningoencephalitis. Serology was positive for Brucella. She was treated with doxycycline, rifampin, and trimethoprim-su...

SYNOPSIS An amoeba of the genus Naegkeria causing fatal meningoencephalitis in a human subject has been investigated for its sensitivity to several drugs. Penicillin, sulphadiazine, chloramphenicol, oxytetracycline hydrochloride, streptomycin, methotrexate, emetine, quinine, and metronidazole had no effect on the organism in vitro at levels in excess of those likely to be attained therapeutical...