Sepsis is a systemic inflammatory response to infection. A common end-feature, these patients regularly suffer from is the so-called multiple organ dysfunction syndrome, an often fatal consequence of organ hypoperfusion, coagulopathy, immune dysregulation,and mitochondrial dysfunction. Microvascular dysfunction critically contributes to the morbidity and mortality of this disease. The angiopoie...

The novel discipline of nutriepigenomics integrates knowledge on nutrigenomics and the reciprocal effects that epigenetic changes exert on gene expression under the influence of nutritional factors. Mutual interactions among genes, nutrients and nutrition-induced epigenetic modifications configure the nutriepigenomic outcome. This trinomial interaction is highly complex and this field is still ...

Verbs fall into a variety of semantic classes. In particular, change of state verbs express events where an “affected” grammatical object undergoes a change of state. Properties of the object as expressed by adjectival modification hold true at the start of the event. The problem of determining if such properties are preserved at event culmination is a sub-case of the well-studied Frame Problem...

Clinical and experimental studies suggest that the growth-restricted fetus at increased risk of impaired cardiovascular function that likely contributes to both increased mortality rate and in survivors, to cardiovascular dysfunction apparent in childhood and later life. Fetal growth restriction is also associated with a high risk of preterm birth. Accordingly, the growth-restricted fetus is mo...

We critically review heavy quark mass effects in DIS and their impact on global analyses. We lay out all elements of a properly defined general mass variable flavor number scheme (GM VFNS) that are shared by all modern formulations of the problem. We then explain the freedom in choosing specific implementations and spell out, in particular, the current formulations of the CTEQ and MSTW groups. ...

Previous research indicated that learners experience an illusion of competence during learning (termed foresight bias) because judgments of learning (JOLs) are made in the presence of information that will be absent at test. The authors examined the following 2 procedures for alleviating foresight bias: enhancing learners' sensitivity to mnemonic cues pertaining to ease of retrieval and inducin...

Teaching students with very diverse backgrounds can be extremely challenging. This article uses the Bioinformatics and Systems Biology MSc in Amsterdam as a case study to describe how the knowledge gap for students with heterogeneous backgrounds can be bridged. We show that a mix in backgrounds can be turned into an advantage by creating a stimulating learning environment for the students. In t...

Latin American has made remarkable progress in the last twenty years regarding LGBTQ+ rights. More recently, LGBTQ-related issues have had major impacts on national and regional politics. However, most of literature about social movements still largely ignores movements. This article argues that including research is essential to further our understanding politics region more broadly, as well a...