crohn’s disease (cd) is rarely presented with lower gi bleeding (lgib) which eludes the clinician. a 25-year-old lady with severe rectorrhagia was presented with no history of constipation, diarrhea or abdominal pain. colonoscopy revealed ulcers in the rectum, sigmoid colon, and terminal ileum. crohn’s pathologic features were detected in the terminal ileum. the bleeding was controlled via supp...

non-alcoholic fatty liver disease (nafld) is the leading cause of chronic liver disease in the united states and other industrialized countries, and the reported prevalence in the developing countries is also rather high. this disease is associated with a high rate of morbidity and mortality and damage to the other organs. the cardiovascular system is, perhaps, the most vulnerable organ to nafl...

background and aims: plant certification programs need reliable, fast, cheap and sensitive methods for detection of systemic pathogens with special interest in virus and viroid detection. reverse transcriptase-polymerase chain reaction (rt-pcr) has been documented as an alternative assay for certification of plant propagating materials. the main object of the present study was the optimization ...

background: celiac disease (cd) has been found in up to 10% of the patients presenting with unexplained abnormal liver function tests (lft). as there is no precise data from our country in this regard, we investigated the prevalence of cd in patients presenting with abnormal lft. methods: from 2003 to 2008, we measured iga anti-tissue transglutaminase (t-tg) antibody (with elisa technique) with...

background: one third of patients with parkinson’s disease (pd) have mentioned “dysphonia” as their most debilitating communication deficit. patient-based measurements, such as voice handicap index (vhi) add necessary supplementary information to clinical and physiological assessment. there are a few studies about relation between vhi and disease severity in pd, although none of them showed any...

case presentation we presented a case of tb lymphadenitis in association with celiac disease that mimicked kfd in a young child. conclusions celiac disease, also known as gluten-sensitive enteropathy and nontropical sprue, is an autoimmune disease with chronic inflammation of small intestine, which is associated with increased risk of tb infection. tb lymphadenitis can mimic kfd. therefore, in ...

case presentation a 28-year old chinese female was treated with carbimazole (cmz) for graves’ disease with hyperthyroidism. two weeks later, she developed myalgia and proximal muscle weakness. investigations showed evidence of myopathy. cmz was stopped and rapid improvement of clinical condition and biochemical parameters ensued. conclusions rapid decrement of thyroid hormone level is recognize...

how to cite this article: karimzadeh p, jafari n, nejad biglari h, jabbeh dari s, ahmad abadi f, alaee mr, nemati h, saket s, tonekaboni sh, taghdiri mm, ghofrani m. gm2-gangliosidosis (sandhoff and tay sachs disease): diagnosis and neuroimaging findings (an iranian pediatric case series) iran j child neurol. 2014 summer;8(3): 55-60.   abstract objective gm2-gangliosidosis disease is a rare aut...

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