IMPORTANCE Subungual melanoma (SM) is a rare subtype of cutaneous melanoma but carries a worse prognosis than similarly staged cutaneous melanomas. Assessing patient knowledge of melanonychia is integral to early diagnosis of SM. OBJECTIVES The aim of this paper is to determine patient knowledge of longitudinal melanonychia (LM) and warning signs for SM, frequency of nail self-examinations, a...

Peutz-Jeghers Syndrome (PJS; MIM 175200) is a rare autosomal dominant syndrome with variable inheritance, characterized by hamartomatous polyps in the gastrointestinal tract, mostly in the small bowel, and pigmented muco-cutaneous lesions (1). Hereditary disorders constitute 70% of PJS cases. The other 30% of cases occur without any previous family history, as a result of spontaneous genetic mu...

328 Ann Dermatol Received April 24, 2014, Revised June 20, 2014, Accepted for publication June 25, 2014 Corresponding author: Dong-Youn Lee, Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Korea. Tel: 82-2-34103543, Fax: 82-2-3410-3869, E-mail: [email protected] This is an Open Access article distributed under t...

Knowledge of the anatomy and function of the nail apparatus is essential when performing the physical examination. Inspection may reveal localized nail abnormalities that should be treated, or may provide clues to an underlying systemic disease that requires further workup. Excessive keratinaceous material under the nail bed in a distal and lateral distribution should prompt an evaluation for o...