PATIENTS AND METHODS: the retrospective study of clinical features and diagnostic tests results included 81 patients with idiopathic megacolon/megarectum (2004–2022). The diagnosis was confirmed a barium enema, Hirschsprung’s disease excluded based on anorectal manometry (if needed) rectal Swenson biopsy. QoL assessed by IBSQOL questionnaire; symptoms were point scale. RESULTS: quality life in ...

Hirschsprung's disease, a congenital condition resulting in functional intestinal obstruction, was seen in 21 children at the University of Calabar Teaching Hospital (UCTH) between January 1996 and December 1998. Late presentation of patients to hospital was observed and was attributed to ignorance and poverty. Patients presented only when repeated herbal enemas no longer offered relief. The ma...

© Zoo Outreach Organisation; www.zoosprint.org Manuscript 1365; Received 23 May 2005; Finally accepted 01 August 2005; Date of publication 21 August 2005 1998 September 2005 | ISSN 0973-2535 (Print edition); 0973-2551 (Online edition) Megacolon refers to the abnormal dilatation of large intestine. It can be a congenital condition caused by the lack of, or incomplete nerve supply to the colon, o...

Statements that the colon is dilated as judged by radiographic appearances have an element of uncertainty because the range of normality is unknown. In this paper an attempt has been made to define the width of the normal colon in statistical terms and the validity of these definitions has been tested by comparison with the diameter of the colon in patients with severe idiopathic proctocolitis ...

Republication of the historical article of Diseases of the Colon & Rectum: Cutait DE, Figliolini FJ. A new method of colorectal anastomosis in abdominoperineal resection. Diseases of the Colon & Rectum. 4(5):335-342, September/October 1961. Read at the meeting of the American Proctologic Society, Pittsburgh, Pennsylvania, June 21 to 24, 1961. † Head of the group in charge of colorectal surgery ...

During a prospective study of infectious gastroenteritis in children under 2 years, 19 out of 390 patients (4.9%) were found to have Clostridium difficile cytotoxin in the faeces. In several there was no history of use of antibiotics. The symptoms of many infants with toxin settled spontaneously, but one child became acutely and severely ill and developed a toxic megacolon and five others requi...

In recent years, cases of elderly-onset ulcerative colitis (UC) have been increasing in number and are currently reported to account for 10-15% of all cases of UC. Although the treatment of UC is essentially similar between older and younger patients, evidence of the therapeutic efficacy of tacrolimus in elderly-onset UC patients is still limited. Herein, we report our attempt to induce remissi...