نتایج جستجو برای: meca gene
تعداد نتایج: 1142208 فیلتر نتایج به سال:
introduction: one of the most important agents in hospital-acquired infections is staphylococcus aureus. treatment of methicillin-resistant s. aureus (mrsa) infections with decreased susceptibility to vancomycin has recently been more difficult. the aim of this study was to evaluate the possible presence of vancomycin intermediate s. aureus (visa) and vancomycin- resistant s. aureus (vrsa) and ...
INTRODUCTION Bovine mastitis is a frequent cause of economic loss in dairy herds. Coagulase-negative staphylococci (CoNS) are increasing in importance as causeof bovine intramammary infection (IMI) throughout the world in recent years. CoNShave been isolated from milk samples collected from cows with clinical andsubclinical mastitis in several countries. Identification of mastitis pathogensis i...
BACKGROUND We compared the LightCycler MRSA advanced test (Roche Diagnostics, Germany) with enrichment culture methods to evaluate the relative diagnostic performance of the LightCycler MRSA advanced test for active surveillance in a high-prevalence setting. METHODS A total of 342 nasal swab specimens were obtained from patients in the intensive care unit at admission and on the seventh day f...
The aim of this study was to determine the prevalence of Staphylococcus aureus and risk factors for the acquisition of MRSA (Methicillin Resistant Staphylococcus aureus) as the main cause of skin and soft tissue infections. S. aureus were characterized for the presence of PVL, TSST-1 and mecA genes. SCCmec typing was carried out in mecA positive strains and PFGE was performed only in these stra...
The prevalence of staphylococci that harbor the mecA gene responsible for methicillin resistance was examined in healthy breeding mares. Staphylococci often cause diseases of horses such as metritis, keratitis, and abscess. Methicillin-resistant staphylococci would make antibiotic treatments ineffective, so it may be significant to know the distribution of mecA-harboring staphylococci in mares....
We describe human cases and clustered animal cases of mecA(LGA251)-positive methicillin-resistant Staphylococcus aureus in France. Our report confirms that this new variant has a large distribution in Europe. It may represent a public health threat because phenotypic and genotypic tests seem unable to detect this new resistance mechanism.
Published Ahead of Print 6 August 2012. 10.1128/AAC.01199-12. 2012, 56(10):4997. DOI: Antimicrob. Agents Chemother. Girbe Buist and Sollid, Joseph F. John Jr., Robert Daum, Bo Soderquist Kreiswirth, Kwan Soo Ko, Hajo Grundmann, Johanna E. Boyle-Vavra, Frederic Laurent, Angela M. Kearns, Barry O'Brien, Fred C. Tenover, Duarte C. Oliveira, Susan Robert L. Skov, Kunyan Zhang, Henrik Westh, Frances...
Resistance to beta-lactam antibiotics in staphylococci is mediated by mecA and blaZ, genes encoding a penicillin-binding protein (PBP2a) with low beta-lactam affinity and beta-lactamase, respectively. The mec and bla regulators, mecR1-mecI and blaR1-blaI, respectively, encode inducer-repressors with sufficient amino acid homology to suggest that they could coregulate PBP2a production. In order ...
BACKGROUND Ventilator-associated pneumonia (VAP) requires prompt and appropriate treatment. Since methicillin-resistant Staphylococcus aureus (MRSA) is a frequent pathogen in VAP, rapid identification of it, is pivotal. Our aim was to evaluate the utility of quantitative polymerase chain reaction (qPCR) as a useful method for etiologic diagnoses of MRSA pneumonia. METHODS We performed qPCR fo...
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