in neonates than any other age group.1 In spite of considerable advances in antimicrobial treatment, neonatal meningitis remains a scourge with a high mortality and frequent permanent neurological sequelae. The causative agents of neonatal sepsis vary between geographical areas and with time in any particular locality. In North America and Europe, the prevalent bacterial agents of early-onset n...

Neonatal septicemia is the most important cause of neonatal mortality. A wide variety of bacteria both aerobic and anaerobic can cause neonatal sepsis. Genus Pantoea is a member of Enterobacteriaceae family that inhabits plants, soil and water and rarely causes human infections, however, Pantoea dispersa has not been reported as a causative organism for neonatal sepsis. We hereby report two neo...

Background: Neonatal sepsis is a clinical syndrome of bacteremia characterized by systemic signs and symptoms infection in the first 28 days life. Although, Positive blood culture gold standard for diagnosis neonatal septicemia, definitive results take at least 48–72 h, resulting treatment delay. Hence certain rapid diagnostic tests such as C-reactive protein, micro erythrocyte sedimentation ra...

Neonatal sepsis is a life-threatening emergency, and any delay in treatment may cause death. Because of the importance of the problem in Iran, the aim of this retrospective study was to determine the etiological agents of neonatal septicemia, and the prevalence and epidemiology of Klebsiella bacteremia in the neonatal wards. Two hundred and ten cases of neonatal sepsis occurred during the study...

Neonatal sepsis continues to be a common and significant health care burden, especially in very-low-birth-weight infants (VLBW<1500 g). Though intrapartum antibiotic prophylaxis has decreased the incidence of early-onset group B streptococcal infection dramatically, it still remains a major cause of neonatal sepsis. Moreover, some studies among VLBW preterm infants have shown an increase in ear...

Blood culture, the gold standard for diagnosis of neonatal sepsis has low sensitivity and is time consuming. Therefore, objective is development and application of Polymerase chain reaction (PCR)-based DNA sequencing to detect and identify bacterium causing neonatal sepsis in culture negative specimens. Sixty three peripheral blood and 8 cerebrospinal fluid (CSF) referred from tertiary level Ne...

OBJECTIVE To determine the validity of C-reactive protein levels for diagnosis of neonatal sepsis. METHODS A cross sectional (Validation) study was conducted at Neonatology unit in KRL general hospital (emergency/OPD) of 7 months duration from February 2012 to August 2012. By using purposive sampling technique, 147, sample size was calculated by using WHO sample size calculator taking sensiti...

BACKGROUND Early onset sepsis remains a major cause for neonatal morbidity and mortality. OBJECTIVES The aim of this study was to describe and compare the clinical and laboratory characteristics of neonates in neonatal intensive care unit with culture positive and negative early onset sepsis and verify if there were any differences between the groups. METHODS A one year comparative prospect...

Neonatal sepsis is a major cause of morbidity and mortality and its signs and symptoms are nonspecific, which makes the diagnosis difficult. The routinely used laboratory tests are not effective methods of analysis, as they are extremely nonspecific and often cause inappropriate use of antibiotics. Sepsis is the result of an infection associated with a systemic inflammatory response with produc...

  Objective(s): Bacterial infection contributes substantially to neonatal morbidity and mortality. Early diagnosis of neonatal sepsis is difficult because clinical signs are non-specific. We have evaluated serum IL-6, 8 and 10 as potential early diagnostic markers of neonatal infection and their relationship to mortality rate and poor prognosis.   Materials and Methods : A total ...