نتایج جستجو برای: mda

تعداد نتایج: 20691  

2017
Tammy Allen Fasihah Taleo Patricia M. Graves Peter Wood George Taleo Margaret C. Baker Mark Bradley Kazuyo Ichimori

BACKGROUND Lymphatic filariasis (LF) occurs when filarial parasites are transmitted to humans through mosquitoes. The filarial worms affect the lymphatic system which leads to abnormal enlargement of body parts, chronic pain, disability, and social discrimination. In 1999, a commitment was made to eliminate LF from the Pacific Region by 2010. The Pacific Program to Eliminate LF began, with Vanu...

2017
Swaathi Jayaraman Michele Doucet Scott L Kominsky

While we previously demonstrated that CITED2 expression in primary breast tumor tissues is elevated relative to normal mammary epithelium and inversely correlated with patient survival, its functional impact on primary tumor development and progression remained unknown. To address this issue, we examined the effect of CITED2 silencing on the growth of human breast cancer cell lines MDA-MB-231 a...

Journal: :Ai zheng = Aizheng = Chinese journal of cancer 2008
Jie Chang Shen Zhang Hui Zhou Jin-Xiao Liang Zhong-Qiu Lin

BACKGROUND & OBJECTIVE The minimal deviation adeno-carcinoma (MDA) of the cervix is a rare disease. The misdiagnosis rate of this disease is relatively high and there is no standard treatment for it. This study was to evaluate clinicopathologic features, diagnosis, and treatment of MDA. METHODS Records of five patients with MDA treated in the Second Affiliated Hospital of Sun Yet-sen Universi...

2013
Thomas Streit Luccene Desir Roland Oscar Jean Frantz Lemoine Nora Colleen Purcell Angela Keller Patrick J. Lammie Michael Deming Valery E. Madsen Beau De Rochars

Lymphatic filariasis (LF), also known as elephantiasis, results from mosquito-borne infection with filarial worm parasites, predominantly Wuchereria bancrofti, and can lead to severe disfigurement from lymphedema and hydrocele. The World Health Organization (WHO) has called for the elimination of LF using the strategy of annual mass drug administration (MDA). WHO defines adequate MDA coverage (...

2012
Xinting Pan Liqun Wu Jingyu Cao Weidong Guo Zusen Wang Bing Han Weiyu Hu

Hepatocellular carcinoma is one of the most common tumors in the world. The purpose of the present study was to investigate the inhibitory effects of adenoviral transduction of human melanoma differentiation-associated gene-7 (MDA-7) gene on hepatocellular carcinoma, so as to provide a theoretical basis for gene therapy of the disease. The human MDA-7 gene was cloned into replication-defective ...

2014
Alexandra Richard-Mazet Sylvain Goutebroze François-Xavier Le Gros David E Swayne Michel Bublot

Inactivated and fowlpox virus (FP)-vectored vaccines have been used to control H5 avian influenza (AI) in poultry. In H5 AI endemic countries, breeder flocks are vaccinated and therefore, maternally-derived antibodies (MDA) are transferred to their progeny. Results of three immunogenicity and one efficacy studies performed in birds with or without MDA indicated that the immunogenicity of an ina...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2008
Moira Sauane Zao-Zhong Su Pankaj Gupta Irina V Lebedeva Paul Dent Devanand Sarkar Paul B Fisher

A noteworthy aspect of melanoma differentiation-associated gene-7/interleukin-24 (mda-7/IL-24) as a cancer therapeutic is its ability to selectively kill cancer cells without harming normal cells. Intracellular MDA-7/IL-24 protein, generated from an adenovirus expressing mda-7/IL-24 (Ad.mda-7), induces cancer-specific apoptosis by inducing an endoplasmic reticulum (ER) stress response. Secreted...

Journal: :Journal of Korea Multimedia Society 2016

Journal: :Cancer research 2005
Habib Boukerche Zao-Zhong Su Luni Emdad Patrick Baril Brigitte Balme Luc Thomas Aaron Randolph Kristoffer Valerie Devanand Sarkar Paul B Fisher

Metastasis is a significant event in cancer progression and continues to pose the greatest challenge for a cancer cure. Defining genes that control metastasis in vivo may provide new targets for intervening in this process with profound therapeutic implications. Melanoma differentiation associated gene-9 (mda-9) was initially identified by subtraction hybridization as a novel gene displaying bi...

2018
Kristjana Hrönn Ásbjörnsdóttir Sitara S Rao Ajjampur Roy M Anderson Robin Bailey Iain Gardiner Katherine E Halliday Moudachirou Ibikounle Khumbo Kalua Gagandeep Kang D Timothy J Littlewood Adrian J F Luty Arianna Rubin Means William Oswald Rachel L Pullan Rajiv Sarkar Fabian Schär Adam Szpiro James E Truscott Marleen Werkman Elodie Yard Judd L Walson

Current control strategies for soil-transmitted helminths (STH) emphasize morbidity control through mass drug administration (MDA) targeting preschool- and school-age children, women of childbearing age and adults in certain high-risk occupations such as agricultural laborers or miners. This strategy is effective at reducing morbidity in those treated but, without massive economic development, ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید