Heart rate and bloody oxygen saturation are significant human's health parameters. This design is a mouse pad monitoring heart rate and oxygen saturation, to reduce the risk of undetected heart state change after concentrating on computer for a long time. Optical power signals reflected by blood are collected by reflective photoelectric sensor, NJL5501R, and then through filtering and amplifica...

The mitochondrial calcium uniporter is a Ca2+-activated Ca2+ channel complex mediating mitochondrial Ca2+ uptake, a process crucial for Ca2+ signaling, bioenergetics, and cell death. The uniporter is composed of the pore-forming MCU protein, the gatekeeping MICU1 and MICU2 subunits, and EMRE, a single-pass membrane protein that links MCU and MICU1 together. As a bridging subunit required for ch...

Type I interferon (IFN-I) is critical for a host against viral and bacterial infections via induction of hundreds of interferon-stimulated genes (ISGs), but the mechanism underlying the regulation of IFN-I remains largely unknown. In this study, we first demonstrate that ISG expression is required for optimal IFN-β levels, an effect that is further enhanced by endoplasmic reticulum (ER) stress....

Mitochondrial Ca(2+) uptake through the recently discovered Mitochondrial Calcium Uniporter (MCU) is controlled by its gatekeeper Mitochondrial Calcium Uptake 1 (MICU1). However, the physiological and pathological role of MICU1 remains unclear. Here we show that MICU1 is vital for adaptation to postnatal life and for tissue repair after injury. MICU1 knockout is perinatally lethal in mice witho...

Bio-sensor arrays for multi-channel recording have been developed recently and signal processing platforms for those signals have been studied actively. But it's thereal situation which these technologies are generally developed and studied respectively. So the interface design between recording array and signal processing platform is also an important issue to make bio-sensor signal processing...

In the paper, a concept and an early analysis of an HW/SW architecture designed to prevent the SW from both timing disturbances and interrupt overloads is outlined. The architecture is composed of an FPGA (MCU) used to run the HW (SW) part of an application. Comparing to previous approaches, novelty of the architecture can be seen in the fact it is able to adapt interrupt service rates to the a...


 The number of industries in a certain region is increasing year by due to the needs people, and therefore intelligent industrialization automation can be used. Here air quality industry products manufactured are monitored using gas detectors (to detect toxic or gases) IR sensors count manufactured) where there no need for labor. Also see estimated time arrival delivery vehicle GPS used g...