BACKGROUND The abundant use of tetracycline antibiotics in veterinary medicine may result in the presence of their residues in milk at unsafe concentrations that can adversely affect public health. The aim of the current study was to evaluate the risk of tetracycline residue (TET) intake via milk consumption amongst different age groups of human consumers in Iran. METHODS To quantify the drug...

MRL/MpJ-Tnfrsf6(lpr) (MRL/MpJ-Fas(lpr); MRL-Fas(lpr)) mice develop a spontaneous lupus syndrome closely resembling human systemic lupus erythematosus. To define the role of IL-10 in the regulation of murine lupus, IL-10 gene-deficient (IL-10(-/-)) MRL-Fas(lpr) (MRL-Fas(lpr) IL-10(-/-)) mice were generated and their disease phenotype was compared with littermates with one or two copies of an int...

Abstract Mycotoxins are secondary metabolites produced by various fungi and known to have a significant negative impact on human animal health. When feedstuffs contaminated with mycotoxins, their toxicities may be caused variety of diseases. In this study, the residual mycotoxins in were analyzed using LC–MS/MS incorporated QuEChERS extraction. Analytical method validation was performed for LOD...

This study was designed to quantify the residual concentrations of some antibiotics such as oxytetracycline (tetracycline), ciprofloxacin (quinolones group), enrofloxacin group) and levofloxacin in broiler production systems. For quantification antibiotic residues (ARs), a rapid, simple accurate method has been developed validated for simultaneous identification oxytetracycline, ciprofloxacin, ...

Extraction and quantification of pesticide residue from the okra matrix at or below established maximum limit (MRL) is a challenging task for both analytical chemists regulatory institutions to take corrective actions human health safety. develop simple rapid less expensive extraction cleanup method simultaneous analysis pyriproxyfen fenpropathrin in two methods: QuEChERS Liquid-Liquid (LLE) we...

The increase of fruit and vegetable (F&V) intake contributes to the prevention of chronic diseases, but could also significantly increase pesticide exposure and may thus be of health concern. Following a previous pesticide exposure assessment study, the present study was carried out to determine actual levels of pesticides within 400 g of F&V intake and to evaluate consumer risk. Forty-three Ac...

In this study, an analysis of pesticide residues was performed using a gas chromatography/ electron impact mass spectrometer (GC/EI-MS) to qualitatively assess and characterize in khat leaves sampled from selected agricultural farms Meru County, Kenya. A solid-phase microextraction (SPME) procedure followed by GC/EI-MS led the detection identification six compounds sample-ion chromatograms. The...

Antibiotic residue in food has been a growing public health problem due to the increasing global threats of antimicrobial resistance. Animal products including milk and meats might also contain residues antibiotics as administering animals treat infection is common practice. However, level presence are not frequently quantified Nepal. The objective this study estimate collected from dairy farms...

We previously reported that difluoromethylornithine (DFMO), an inhibitor of polyamine biosynthesis, exerted significant beneficial effects on the lifespan and disease expression of MRL-lpr/lpr mice, which spontaneously develop a lupus-like syndrome. Polyamine levels in splenic T-cells of MRL-lpr/lpr mice were significantly higher than those of Balb/c mice. In the present investigation, we exami...