BACKGROUND:Teratoma, a tumor containing variety of tissues, is broad diagnosis mature teratoma, immature and teratomas with malignant transformation. The forms during embryological development secondary to unsuccessful migration primordial germ cells. A specific type human-like features, called fetiform teratoma. teratoma often compared confused fetus in fetu, reabsorbed twin. While these tumor...

to describe the morphological and histological changes during the annual reproductive cycle of the gonads of cyprinion tenuiradius, a total of 341 specimens (102 female and 235 male specimens) were collected monthly from the rudbal river (in the qarah aghaj sub-basin, the persian gulf basin), firuzabad, fars province, southern iran. the randomly sampling was adequate to collect males and female...

BACKGROUND Gonadoblastoma (GB) is regarded as an in situ form of germ cell tumor in dysgenetic gonads, and 30% of patients with GB develop a dysgerminoma/seminoma tumor. OBJECTIVE Determine whether OCT3/4 and β-catenin are expressed in dysgenetic gonads before GB development and whether TSPY participates in the OCT3/4-β-catenin pathways in the malignant invasive behavior. METHODS dysgenetic...

In order to isolate genes regulating sex differentiation of embryonic gonads, we have attempted to obtain genes specifically expressed in male embryonic gonads by means of subtractive hybridization screening, and we have cloned a novel mouse gene, Tdl. It potentially encodes a protein showing sequence homology to anti-microbial protein, beta-defensins. Tdl reveals structural features such as th...

A 33-year-old phenotypic female presented with primary amenorrhea. The physical examination revealed no breast development, scanty axillary and pubic hair, normal female external genitalia, and a short blind vagina. The findings of magnetic resonance imaging, karyotyping, and hormonal examinations supported the diagnosis of XY partial gonadal dysgenesis. Laparoscopic surgery showed that spermat...

In Drosophila melanogaster, the expression of adenosine deaminase acting on RNA is regulated by transcription and alternative splicing so that at least four different isoforms are generated that have a tissue-specific splicing pattern. Even though dAdar has been extensively studied, the complete adult expression pattern has yet to be elucidated. In the present study, we investigate mature trans...

In vertebrates, one of the first recognizable sex differences in embryos is the onset of meiosis, known to be regulated by retinoic acid (RA) in mammals. We investigated in medaka a possible meiotic function of RA during the embryonic sex determination (SD) period and in mature gonads. We found RA mediated transcriptional activation in germ cells of both sexes much earlier than the SD stage, ho...

This study attempts to look into the energetic status of demersal fish species with their maturity stages and evaluate their energetic condition. Demersal fish species from wild were captured, total length and weight of each fish were measured and gonads were observed, weighted and collected with fish flesh. Gonadosomatic index, water content of gonad and flesh and gonadal and somatic caloric v...

Sex differentiation process, determination of sexual strategy, and gametogenesis of the annual fish Austrolebias charrua are established. Evidence of histological sex differentiation in an antero-posterior gradient was observed in pre-hatching stages. Sexual strategy corresponds to the "differentiated gonochoric" pattern. Histological analyses of adult gonads showed an asynchronous spawning mod...

FHX (FOXJ2) is a recently characterized human fork head transcriptional activator that binds DNA with a dual sequence specificity. We have cloned the cDNA for the mouse orthologue Foxj2 and characterized its expression in the gonads and along the early pre-implantation development of the mouse. In the testis, Foxj2 is expressed from pachytene spermatocytes to round spermatids, but not in sperma...