A p-hub center network design problem is definition of some nodes as hubs and allocation of non-hub nodes to them wherein the maximum travel times between any pair of nodes is minimized. The distinctive feature of this study is proposing a new mathematical formulation for modeling costs in a p-hub center problem. Here, instead of considering costs as a linear function of distance, for the first...

This paper presents a learning and inference mechanism for unsupervised learning of semantic concepts from purely syntactical examples of design optimization formulation data. Symbolic design formulation is a tough problem from computational and cognitive perspectives, requiring domain and mathematical expertise. By conceptualizing the learning problem as a statistical pattern extraction proble...

      Extended release formulation of alfuzosin, an a-antagonist used for prostatic hypertrophy, is available in market. It is convenient for older patients to take only one tablet a day. Marketed alfuzosin formulation is three layered geomatrix tablet that requires special facilities, high cost, more time and complex operation than normal direct compression formulation. Therefore, a less compl...

In this paper power system model is represented in a new domain that relates to Multi-Resolution Analysis (MRA) space. By developing mathematical model of elements in this space using Galerkin method, a new alternative method for power system simulation in nonsinusoidal and periodic conditions is developed. The mathematical formulation and characteristics of new proposed space is expressed. Als...

After a brief introduction to the spectral analysis of saddle point matrices, in this talk we present new estimates for the eigenvalue intervals for symmetric saddle-point and regularised saddle-point matrices in the case where the (1,1) block may be indefinite. These generalise known results for the definite (1,1) case. We also discuss spectral properties of the equivalent augmented formulatio...

The formation of liver zones is modeled by a system of two integropartial differential equations. In this research, we introduce the mathematical formulation of these integro-partial differential equations obtained by Bass et al. in 1987. For better understanding of this mathematical formulation, we present a medical introduction for the liver in order to make the formulation as clear as possib...

Although reconciliation of steady-state process data is routinely applied in industrial practice, the theoretical understanding of the problem and its adequate formulation in a dynamic setting is still not mature. Existing formulation approaches are based on stochastic lters, deterministic observers or mathematical programming techniques. In this contribution, we suggest a general problem formu...

We developed methods to integrate two published models that partitioned gains in empty body weight (EBW) to fat and fat-free matter. These models were based on separate mathematical formulations for growing and mature cattle. We assumed that as cattle grow from birth to maturity a transition would occur at some point in the life cycle from the growing to the mature mathematical formulation. Thi...

The objectives of this study were (a) To Perform in-vitro release study of marketed Nifedipine formulation,(b) To check effect of integrity on release profiles, (c) To determine the possibility of switchover from one formulation to another formulation and (d) To compare release profiles with formulated batches by application of mathematical models. Four marketed and two prepared controlled rele...