نتایج جستجو برای: maternal exposure
تعداد نتایج: 402838 فیلتر نتایج به سال:
Maternal occupational pesticide exposure during pregnancy and/or paternal occupational pesticide exposure around conception have been suggested to increase risk of leukemia in the offspring. With a view to providing insight in this area we pooled individual level data from 13 case-control studies participating in the Childhood Leukemia International Consortium (CLIC). Occupational data were har...
BACKGROUND Airborne polycyclic aromatic hydrocarbons (PAHs) are pollutants generated by combustion of fossil fuel and other organic material. Both prenatal PAH exposure and maternal psychological distress during pregnancy have each been associated with neurodevelopmental problems in children. The goal was to evaluate potential interactions between prenatal exposure to airborne PAHs and maternal...
Brief summary: Using placental perfusion, fragment culture and primary term human cytotrophoblast experiments, the authors signify relationship between maternal vitamin D, D metabolism fetal exposure.
Exposure to non-inherited maternal antigens (NIMA) has life-long immunological consequences that may result in tolerance or immunity to these antigens. Gaining understanding of the mechanisms behind these NIMA effects will impact many areas of immunology. This review summarizes new discoveries relevant to autoimmunity and organ transplantation regarding exposure to maternal antigens. In light o...
To assess teratogenic effects of cocaine exposure and maternal psychological distress on birth outcomes, we conducted a longitudinal prospective study of 415 infants (218 cocaine-exposed--CE, 197 nonexposed--NE). Drug exposure was determined through a combination of maternal self-report, urine, and meconium screens. Maternal psychological distress postpartum was evaluated through a standardized...
Maternal ethanol intake during pregnancy impairs fetal growth, but mechanisms are not clearly defined. Reduced IGF abundance or bioavailability in the fetus and/or mother may contribute to this growth restriction. We hypothesized that an episode of acute ethanol exposure, mimicking binge drinking would restrict fetal growth and perturb the maternal and fetal IGF axes. Pregnant sheep were infuse...
BACKGROUND The impact of maternal ingestion of peanut during pregnancy and lactation on an offspring's risk for peanut allergy is under debate. OBJECTIVE To investigate the influence of maternal dietary peanut exposure and breast milk on an offspring's allergy risk. METHODS Preconceptionally peanut-exposed C3H/HeJ females were either fed or not fed peanut during pregnancy and lactation. The...
background & objectives: cryptorchidism is one of the most common congenital anomalies at birth. cryptorchidism is an abnormally positioned testis. the undescended testis can be located anywhere between the abdominal cavity and just outside the anatomical scrotum. this study was conducted to determine some etiologic factors in cryptorchidism. materials & methods: in an analytical cross-sectiona...
Exposure to maternal obesity before and/or throughout pregnancy may increase the risk of obesity and insulin resistance in the offspring in childhood and adult life, therefore, resulting in its transmission into subsequent generations. We have previously shown that exposure to maternal obesity around the time of conception alone resulted in increased adiposity in female lambs. Changes in the ab...
The authors examined the effects of maternal intrauterine undernutrition on offspring birth weights in a cohort of women born between August 1944 and April 1946 in Amsterdam, The Netherlands. This period included the Dutch Hunger Winter, a war-induced famine. Undernutrition was defined separately for each trimester of pregnancy as an average supply of less than 1,000 calories per day from gover...
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